Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | LAP3 | P28838 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | PTGES | O14684 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1222497 | 0.86 | ALDH1A1 (0.43) | ALDH1A1KMT2AHTTMEN1LMNA | |
| SCHEMBL15865596 | 0.81 | AAK1 (0.43) | ALDH1A1ELANEKMT2AHTTMEN1 | |
| SCHEMBL12884492 | 0.78 | PIN1 (0.39) | ALDH1A1KMT2AHTTMEN1LMNA | |
| SCHEMBL8657646 | 0.70 | ALDH1A1 (0.47) | ALDH1A1KMT2AHTTMEN1LMNA | |
| SCHEMBL1621780 | 0.70 | ALDH1A1 (0.47) | ALDH1A1KMT2AMEN1L3MBTL1LMNA | |
| SCHEMBL30468543 | 0.70 | ALDH1A1 (0.47) | ALDH1A1KMT2AMEN1L3MBTL1LMNA | |
| SCHEMBL25592222 | 0.67 | L3MBTL1 (0.50) | ALDH1A1KMT2AMEN1TSHRL3MBTL1 | |
| SCHEMBL30458214 | 0.65 | ALDH1A1 (0.49) | ALDH1A1ELANEKMT2AMEN1MAOB | |
| SCHEMBL21857352 | 0.65 | PIN1 (0.56) | KMT2AMEN1MAOBPTGESLMNA | |
| SCHEMBL29457514 | 0.65 | PIN1 (0.56) | KMT2AMEN1MAOBPTGESLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009132774-A1 | NEW SUBSTITUTED INDOLIN-2-ONE DERIVATIVES AND THEIR USE AS P39 MITOGEN-ACTIVATED KINASE INHIBITORS | ALMIRALL, S. A. (ES) | 2009-11-05 | — | — | WO | disclosed |