Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.39 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RIPK2 | O43353 | 4/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
| ▸ | ATIC | P31939 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12702614 | 0.81 | LMNA (0.69) | LMNAALDH1A1PI4KAPI4K2BPI4K2A | |
| SCHEMBL21515841 | 0.81 | ALDH1A1 (0.69) | LMNAALDH1A1PI4KAPI4K2BPI4K2A | |
| SCHEMBL12702849 | 0.80 | LMNA (0.67) | LMNAALDH1A1PI4KAPI4K2BPI4K2A | |
| SCHEMBL31352259 | 0.77 | ALDH1A1 (0.62) | LMNAALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL19569889 | 0.77 | ALDH1A1 (0.61) | LMNAALDH1A1KDM4ETDP1TP53 | |
| SCHEMBL19968861 | 0.76 | ALDH1A1 (0.61) | LMNAALDH1A1PI4KAPI4K2BPI4K2A | |
| SCHEMBL12702668 | 0.75 | ALDH1A1 (0.60) | LMNAALDH1A1PI4KAPI4K2BPI4K2A | |
| SCHEMBL25074041 | 0.75 | ALDH1A1 (0.59) | LMNAALDH1A1PI4KAPI4K2BPI4K2A | |
| SCHEMBL21372045 | 0.75 | ALDH1A1 (0.59) | LMNAALDH1A1PI4KAPI4K2BPI4K2A | |
| SCHEMBL23188727 | 0.75 | ALDH1A1 (0.59) | LMNAALDH1A1PI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210170043-A1 | DC-SIGN ANTIBODY CONJUGATES COMPRISING STING AGONISTS | CHINOOK THERAPEUTICS, INC. | 2021-06-10 | — | — | US | disclosed |
| US-8415321-B2 | Nucleoside derivatives for treatment of Caliciviridae infections, including Norovirus infections | THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS | 2013-04-09 | — | — | US | disclosed |
| US-20090280084-A1 | NUCLEOSIDE DERIVATIVES FOR TREATMENT OF CALICIVIRIDAE INFECTIONS, INCLUDING NOROVIRUS INFECTIONS | THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS | 2009-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090280084-A1 | NUCLEOSIDE DERIVATIVES FOR TREATMENT OF CALICIVIRIDAE INFECTIONS, INCLUDING NOROVIRUS INFECTIONS | PNP, NUDT1, RNMT | LMNA 2245/4885ALDH1A1 3010/4885PI4KA 1528/4885 |
| US-20210170043-A1 | DC-SIGN ANTIBODY CONJUGATES COMPRISING STING AGONISTS | STING1, TLR9, TLR3 | LMNA 2865/4885ALDH1A1 4425/4885PI4KA 3182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.