SCHEMBL13618325

SCHEMBL13618325

CO[C@H]1[C@@H](O)[C@H](n2ccc(=O)[nH]c2=O)O[C@@H]1[C@@H](O[C@H]1OC(C(=O)Nc2ccc(F)c(F)c2)=C[C@H](O)[C@@H]1O)C(N)=O

nearest known ligand 0.74

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DPAGT1 Q9H3H5 5/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14599001 0.95 DPAGT1 (0.62) DPAGT1
SCHEMBL14599011 0.94 DPAGT1 (0.59) DPAGT1
SCHEMBL13618332 0.93 DPAGT1 (0.58) DPAGT1
SCHEMBL14598996 0.92 DPAGT1 (0.63) DPAGT1
SCHEMBL13618328 0.92 DPAGT1 (0.61) DPAGT1
SCHEMBL14599051 0.92 DPAGT1 (0.57) DPAGT1
SCHEMBL14628910 0.90 DPAGT1 (0.52) DPAGT1
SCHEMBL14598997 0.90 DPAGT1 (0.63) DPAGT1
SCHEMBL14598994 0.90 DPAGT1 (0.65) DPAGT1
SCHEMBL13618327 0.89 DPAGT1 (0.60) DPAGT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144674-A1 Apparatus and Methods for Drug Delivery Using Microneedles CLEARSIDE BIOMEDICAL, INC. (US) 2026-05-28 US disclosed
US-20250345206-A1 APPARATUS AND METHODS FOR OCULAR INJECTION CLEARSIDE BIOMEDICAL, INC. (US) 2025-11-13 US disclosed
US-12350261-B2 Methods and devices for the treatment of ocular diseases in human subjects CLEARSIDE BIOMEDICAL, INC. (US) 2025-07-08 US disclosed
US-20250186253-A1 DEVICES AND METHODS FOR ADJUSTING THE INSERTION DEPTH OF A NEEDLE FOR MEDICAMENT DELIVERY CLEARSIDE BIOMEDICAL, INC. (US) 2025-06-12 US disclosed
EP-4566672-A2 METHODS FOR THE TREATMENT OF OCULAR DISEASE IN HUMAN SUBJECTS Clearside Biomedical Inc. (US) 2025-06-11 EP disclosed
EP-3554435-B1 SYSTEMS FOR DELIVERING DRUGS TO RETINAL TISSUE CLEARSIDE BIOMEDICAL INC (US) 2025-06-04 EP disclosed
US-20250152413-A1 SYSTEMS, DEVICES, AND METHODS FOR NEEDLE-LESS OCULAR INJECTIONS CLEARSIDE BIOMEDICAL INC (US) 2025-05-15 US disclosed
EP-3721872-B1 METHODS FOR THE TREATMENT OF OCULAR DISEASE IN HUMAN SUBJECTS CLEARSIDE BIOMEDICAL INC (US) 2025-01-22 EP disclosed
US-12201558-B2 Apparatus and methods for ocular injection CLEARSIDE BIOMEDICAL, INC. (US) 2025-01-21 US disclosed
US-12127975-B2 Devices and methods for adjusting the insertion depth of a needle for medicament delivery CLEARSIDE BIOMEDICAL, INC. (US) 2024-10-29 US disclosed
US-11596545-B2 Systems and methods for ocular drug delivery CLEARSIDE BIOMEDICAL, INC. (US) 2023-03-07 US disclosed
US-11559428-B2 Apparatus and methods for ocular injection CLEARSIDE BIOMEDICAL, INC. (US) 2023-01-24 US disclosed
EP-2887982-B1 APPARATUS FOR DRUG DELIVERY USING MICRONEEDLES CLEARSIDE BIOMEDICAL INC (US) 2022-11-23 EP disclosed
US-11504431-B2 Formulations for the suprachoroidal space of an eye and methods EMORY UNIVERSITY (US) 2022-11-22 US disclosed
US-20220280341-A1 APPARATUS AND METHODS FOR DRUG DELIVERY USING MICRONEEDLES CLEARSIDE ROYALTY LLC 2022-09-08 US disclosed
US-20220280386-A1 METHODS AND APPARATUS FOR EXTRACTING FLUID FROM CONTAINER CLEARSIDE BIOMEDICAL, INC. 2022-09-08 US disclosed
WO-2022076938-A1 APPARATUS AND METHODS OF RETINAL INJECTION CLEARSIDE BIOMEDICAL, INC. (US) 2022-04-14 WO disclosed
WO-2009136965-A1 COMPOSITIONS AND METHODS COMPRISING CAPURAMYCIN ANALOGUES SEQUELLA, INC. (US) 2009-11-12 WO disclosed
US-20090281054-A1 COMPOSITIONS AND METHODS COMPRISING CAPURAMYCIN ANALOGUES SEQUELLA, INC. 2009-11-12 US disclosed
US-7157442-B2 Antibacterial compound SANKYO COMPANY, LIMITED (JP) 2007-01-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260144674-A1 Apparatus and Methods for Drug Delivery Using Microneedles PROKR2, SLC10A2, GLP1R DPAGT1 4189/4885
US-20090281054-A1 COMPOSITIONS AND METHODS COMPRISING CAPURAMYCIN ANALOGUES TTPA, PHOSPHO1, CAPG DPAGT1 309/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.