Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 2/20 | 0.39 |
| ▸ | CCND1 | P24385 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13618524 | 0.79 | HTT (0.70) | HSP90AA1ALDH1A1HPGDHTTLMNA | |
| SCHEMBL28280163 | 0.79 | HTT (0.42) | HSP90AA1ALDH1A1HPGDHTTLMNA | |
| SCHEMBL22551122 | 0.79 | HTT (0.55) | ALDH1A1HPGDHTTLMNAKMT2A | |
| SCHEMBL1662914 | 0.76 | GAA (0.59) | ALDH1A1HPGDHTTKMT2ATSHR | |
| SCHEMBL7469385 | 0.75 | HPGD (0.56) | ALDH1A1HPGDLMNACYP2C9TSHR | |
| SCHEMBL13618698 | 0.73 | L3MBTL3 (0.43) | ALDH1A1TSHRRAB9A | |
| SCHEMBL24696444 | 0.71 | CYP2C19 (0.50) | ALDH1A1HTTLMNACYP2C9CYP2C19 | |
| SCHEMBL7047272 | 0.70 | HPGD (0.63) | ALDH1A1HPGDLMNAKMT2ATSHR | |
| SCHEMBL14061385 | 0.69 | HSP90AA1 (0.53) | HSP90AA1ALDH1A1HPGDHTTLMNA | |
| SCHEMBL1929985 | 0.69 | HTT (0.70) | ALDH1A1HPGDHTTCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140467-A1 | OXOBENZINDOLIZINOQUINOLINES AND USES THEREOF | PURDUE RESEARCH FOUNDATION (US) | 2009-11-19 | — | — | WO | disclosed |