Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.42 |
| ▸ | ACLY | P53396 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 3/20 | 0.36 |
| ▸ | RXRG | P48443 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1336759 | 0.78 | GABRA1 (0.50) | GABRA1GABRB2HDAC3HDAC6ACLY | |
| SCHEMBL93161 | 0.76 | GABRA1 (0.69) | GABRA1GABRB2MAPTKDM4EGAA | |
| SCHEMBL8116484 | 0.76 | GABRA1 (0.48) | GABRA1GABRB2HDAC3HDAC6ACLY | |
| SCHEMBL9516534 | 0.74 | GABRA1 (0.46) | GABRA1GABRB2HDAC3HDAC6ACLY | |
| SCHEMBL28479006 | 0.74 | GABRA1 (0.46) | GABRA1GABRB2HDAC3HDAC6ACLY | |
| SCHEMBL16628066 | 0.74 | MAPT (0.50) | HDAC3HDAC6MAPTHDAC8HDAC1 | |
| SCHEMBL17931815 | 0.74 | GABRA1 (0.46) | GABRA1GABRB2HDAC3HDAC6ACLY | |
| SCHEMBL13617224 | 0.74 | LMNA (0.52) | HDAC3HDAC6MAPTHDAC8HDAC1 | |
| SCHEMBL16259491 | 0.73 | MAPT (0.55) | GABRA1GABRB2HDAC3HDAC6MAPT | |
| SCHEMBL2346923 | 0.73 | GPR35 (0.47) | GABRA1GABRB2HDAC3HDAC6ACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2113548-B1 | ORGANIC ELECTROLUMINESCENCE DEVICE | UDC IRELAND LTD (IE) | 2016-05-25 | — | — | EP | disclosed |
| CN-103080269-B | Photochromic composition | TOKUYAMA CORP. (JP) | 2015-12-16 | — | — | CN | disclosed |
| CN-103080269-A | Photochromic composition | TOKUYAMA CORP | 2013-05-01 | — | — | CN | disclosed |
| EP-2113548-A1 | Organic electroluminescence device | FUJIFILM Corporation (JP) | 2009-11-04 | — | — | EP | disclosed |