SCHEMBL16259491

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16259489	0.90	MAPT (0.70)	MAPTHTTRAB9ANPC1MAPK1
	SCHEMBL28854422	0.88	ALDH1A1 (0.51)	MAPTHTTRAB9ANPC1MAPK1
	SCHEMBL2346923	0.86	GPR35 (0.47)	MAPTHTTRAB9ANPC1MAPK1
	SCHEMBL14200242	0.84	ALDH1A1 (0.60)	MAPTHTTSMN1; SMN2MEN1KMT2A
	SCHEMBL16259464	0.83	MAPT (0.51)	MAPTHTTRAB9ANPC1MAPK1
	SCHEMBL7758352	0.83	KIF11 (0.59)	MAPTNPC1GABRA1GABRB2HDAC3
	SCHEMBL27799352	0.81	SMN1; SMN2 (0.47)	MAPTHTTRAB9ANPC1MAPK1
	SCHEMBL16106347	0.80	KCNK9 (0.46)	MAPTHTTRAB9ANPC1MAPK1
	SCHEMBL32675964	0.79	RAF1 (0.65)	MAPTHTTRAB9ANPC1MAPK1
	SCHEMBL2681462	0.77	MAPT (0.78)	MAPTHTTRAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.