Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | BRS3 | P32247 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13618879 | 0.98 | TAS1R3 (0.37) | FFAR1CXCR5TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL13618871 | 0.97 | TAS1R3 (0.36) | FFAR1CXCR5TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL13618888 | 0.82 | NPC1 (0.34) | CXCR5TAS1R3TAS1R1TAS1R2ALDH1A1 | |
| SCHEMBL13618884 | 0.81 | LMNA (0.37) | ACKR3KDM4ENPC1TP53RAB9A | |
| SCHEMBL13618887 | 0.81 | HDAC1 (0.36) | FFAR1ACKR3NPC1HPGDRAB9A | |
| SCHEMBL13618875 | 0.80 | LMNA (0.39) | ACKR3KDM4ENPC1TP53RAB9A | |
| SCHEMBL13618877 | 0.80 | HDAC1 (0.37) | ACKR3KDM4ENPC1HPGDRAB9A | |
| SCHEMBL13618880 | 0.78 | HSD17B1 (0.43) | CXCR5TAS1R3TAS1R1TAS1R2ALDH1A1 | |
| SCHEMBL13618872 | 0.77 | HSD17B1 (0.45) | CXCR5TAS1R3TAS1R1TAS1R2ALDH1A1 | |
| SCHEMBL13618873 | 0.71 | MEN1 (0.33) | FFAR1ALDH1A1KDM4ENPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090286765-A1 | Therapeutic Agents | MERCK SHARP & DOHME (UK) LIMITED (GB) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286765-A1 | Therapeutic Agents | GRIA1, GRIN1, GLRA1 | FFAR1 1134/4885CXCR5 4708/4885TAS1R3 1314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.