Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13489710 | 1.00 | CA1 (0.40) | CA1CA2CA7HTTKMT2A | |
| SCHEMBL13618938 | 0.85 | — | — | |
| SCHEMBL13619134 | 0.85 | ALDH1A1 (0.41) | CA1CA2CA7HTTKMT2A | |
| SCHEMBL15764467 | 0.85 | HSD17B10 (0.44) | CA1CA2CA7HTTKMT2A | |
| SCHEMBL13619136 | 0.85 | ALDH1A1 (0.41) | CA1CA2CA7HTTKMT2A | |
| SCHEMBL15558022 | 0.84 | HSD17B10 (0.43) | CA1CA2CA7HTTKMT2A | |
| SCHEMBL26302740 | 0.84 | HSD17B10 (0.43) | CA1CA2CA7HTTKMT2A | |
| SCHEMBL15598084 | 0.83 | CA1 (0.38) | CA1CA2CA7HTTKMT2A | |
| SCHEMBL16822817 | 0.83 | CA1 (0.38) | CA1CA2CA7HTTKMT2A | |
| SCHEMBL15558416 | 0.83 | CTSS (0.41) | CA1CA2CA7HTTCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9133141-B2 | Cysteine and cystine bioisosteres to treat schizophrenia and reduce drug cravings | MARQUETTE UNIVERSITY (US) | 2015-09-15 | — | — | US | disclosed |
| US-9133141-B2 | Cysteine and cystine bioisosteres to treat schizophrenia and reduce drug cravings | MARQUETTE UNIVERSITY (US) | 2015-09-15 | — | — | US | disclosed |
| US-20140155440-A1 | CYSTEINE AND CYSTINE BIOISOSTERES TO TREAT SCHIZOPHRENIA AND REDUCE DRUG CRAVINGS | MARQUETTE UNIVERSITY (US) | 2014-06-05 | — | — | US | disclosed |
| US-20140155440-A1 | CYSTEINE AND CYSTINE BIOISOSTERES TO TREAT SCHIZOPHRENIA AND REDUCE DRUG CRAVINGS | MARQUETTE UNIVERSITY (US) | 2014-06-05 | — | — | US | disclosed |
| WO-2009137251-A2 | CYSTEINE AND CYSTINE BIOISOSTERES TO TREAT SCHIZOPHRENIA AND REDUCE DRUG CRAVINGS | MARQUETTE UNIVERSITY (US) | 2009-11-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140155440-A1 | CYSTEINE AND CYSTINE BIOISOSTERES TO TREAT SCHIZOPHRENIA AND REDUCE DRUG CRAVINGS | CTH, CBS, SLC7A11 | CA1 1760/4885CA2 3051/4885CA7 2705/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.