Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30116202 | 0.92 | OPRM1 (0.37) | CA2 | |
| SCHEMBL8063012 | 0.90 | FAAH (0.37) | CA2 | |
| SCHEMBL25899583 | 0.90 | — | — | |
| SCHEMBL16928574 | 0.90 | — | — | |
| SCHEMBL25899579 | 0.90 | — | — | |
| SCHEMBL15508041 | 0.90 | — | — | |
| SCHEMBL8072842 | 0.89 | CA2 (0.40) | CA2 | |
| SCHEMBL4820816 | 0.87 | CA2 (0.31) | CA2 | |
| SCHEMBL4820847 | 0.87 | — | — | |
| SCHEMBL4820811 | 0.87 | CA2 (0.31) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7615543-B2 | Complexes with C-reactive protein (CRP) molecules; rheumatoid arthritis, juvenile chronic (rheumatoid) arthritis, ankylosing spondylitis, psoriatic arthritis, systemic vasculitis, polymyalgia rheumatica, Reiter's disease, Crohn's disease and familial Mediterranean fever | PENTRAXIN THERAPEUTICS LIMITED (GB) | 2009-11-10 | — | — | US | disclosed |