SCHEMBL8063012

SCHEMBL8063012

CCCCCCC(C)O[Si](C)(C)C(C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FAAH O00519 5/20 0.37
CNR1 P21554 1/20 0.36
CNR2 P34972 1/20 0.36
ALDH1A1 P00352 1/20 0.36
OPRM1 P35372 1/20 0.35
CA2 P00918 2/20 0.35
SPHK1 Q9NYA1 1/20 0.34
LMNA P02545 1/20 0.33
NAAA Q02083 1/20 0.33
ADH1B P00325 1/20 0.32
ADH1C P00326 1/20 0.32
ADH1A P07327 1/20 0.32
ADH4 P08319 1/20 0.32
ADH7 P40394 1/20 0.32
DNM1 Q05193 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30116202 0.98 OPRM1 (0.37) FAAHCNR1CNR2ALDH1A1OPRM1
SCHEMBL8072842 0.92 CA2 (0.40) CA2DNM1
SCHEMBL13619245 0.90 CA2 (0.31) CA2
SCHEMBL15508258 0.86 TSHR (0.34) CA2SPHK1
SCHEMBL2054509 0.84 CA2 (0.33) CA2
SCHEMBL14834118 0.82 CA2 (0.36) OPRM1CA2LMNADNM1
SCHEMBL31243817 0.82 MAPK1 (0.49) ALDH1A1LMNA
SCHEMBL19054616 0.81 CA2 (0.36) CA2
SCHEMBL15508041 0.81
SCHEMBL16928574 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000050478-A1 NOVEL FORMULATIONS OF ALKYLLITHIUMS WITH IMPROVED THERMAL STABILITY, PROCESSES TO PRODUCE THESE FORMULATIONS AND PROCESSES FOR USING THE SAME TO IMPROVE STABILITY OF LIVING POLYMER CHAIN ENDS FMC CORPORATION (US) 2000-08-31 WO claimed
EP-1023333-A1 PROCESSES FOR IMPROVING STABILITY OF LIVING POLYMERIZATION CHAIN ENDS FMC CORPORATION (US) 2000-08-02 EP claimed
WO-1999012979-A1 PROCESSES FOR IMPROVING STABILITY OF LIVING POLYMERIZATION CHAIN ENDS FMC CORPORATION (US) 1999-03-18 WO claimed
US-9643958-B2 Deprotection method for protected hydroxyl group ASAHI GLASS COMPANY, LIMITED (JP) 2017-05-09 US disclosed
EP-2700628-B1 DEPROTECTION METHOD FOR PROTECTED HYDROXYL GROUP ASAHI GLASS CO LTD (JP) 2016-09-14 EP disclosed
US-20140058113-A1 DEPROTECTION METHOD FOR PROTECTED HYDROXYL GROUP ASAHI GLASS COMPANY, LIMITED (JP) 2014-02-27 US disclosed
EP-2700628-A1 DEPROTECTION METHOD FOR PROTECTED HYDROXYL GROUP Asahi Glass Company, Limited (JP) 2014-02-26 EP disclosed
WO-2000050478-A1 NOVEL FORMULATIONS OF ALKYLLITHIUMS WITH IMPROVED THERMAL STABILITY, PROCESSES TO PRODUCE THESE FORMULATIONS AND PROCESSES FOR USING THE SAME TO IMPROVE STABILITY OF LIVING POLYMER CHAIN ENDS FMC CORPORATION (US) 2000-08-31 WO disclosed
EP-1023333-A1 PROCESSES FOR IMPROVING STABILITY OF LIVING POLYMERIZATION CHAIN ENDS FMC CORPORATION (US) 2000-08-02 EP disclosed
WO-1999012979-A1 PROCESSES FOR IMPROVING STABILITY OF LIVING POLYMERIZATION CHAIN ENDS FMC CORPORATION (US) 1999-03-18 WO disclosed
WO-1996012723-A1 PROCESS FOR PREPARING ALKYLSILYL OR ARYLSILYL ETHERS FMC CORPORATION (US) 1996-05-02 WO disclosed
US-5493044-A Process for preparing alkylsilyl or arylsilyl ethers FMC CORPORATION (US) 1996-02-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140058113-A1 DEPROTECTION METHOD FOR PROTECTED HYDROXYL GROUP ADH1C, ADH1A, ADH5 FAAH 539/4885CNR1 3170/4885CNR2 2196/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.