Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.58 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.51 |
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.45 |
| ▸ | TRPV3 | Q8NET8 | 5/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15780394 | 1.00 | LTA4H (0.58) | LTA4HFUCA1KDM1AMAOACD274 | |
| SCHEMBL28709021 | 1.00 | LTA4H (0.58) | LTA4HFUCA1KDM1AMAOACD274 | |
| SCHEMBL15921601 | 1.00 | LTA4H (0.58) | LTA4HFUCA1KDM1AMAOACD274 | |
| SCHEMBL697762 | 1.00 | LTA4H (0.58) | LTA4HFUCA1KDM1AMAOACD274 | |
| SCHEMBL1755583 | 1.00 | LTA4H (0.58) | LTA4HFUCA1KDM1AMAOACD274 | |
| SCHEMBL14001426 | 1.00 | LTA4H (0.58) | LTA4HFUCA1KDM1AMAOACD274 | |
| SCHEMBL697761 | 1.00 | LTA4H (0.58) | LTA4HFUCA1KDM1AMAOACD274 | |
| Hydrochloric Acid SCHEMBL3337665 | 0.98 | LTA4H (0.56) | LTA4HFUCA1KDM1AMAOACD274 | |
| Hydrochloric Acid SCHEMBL3337659 | 0.98 | LTA4H (0.56) | LTA4HFUCA1KDM1AMAOACD274 | |
| Hydrochloric Acid SCHEMBL3337663 | 0.98 | LTA4H (0.56) | LTA4HFUCA1KDM1AMAOACD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114315609-B | Technological method for preparing cis-2-aminocyclohexanol | 大连双硼医药化工有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-114315609-A | Process for preparing cis-2-aminocyclohexanol | 大连双硼医药化工有限公司 | 2022-04-12 | — | — | CN | disclosed |
| EP-2951180-B1 | 2,6,7,8 SUBSTITUTED PURINES AS HDM2 INHIBITORS | MERCK SHARP & DOHME (US) | 2018-05-02 | — | — | EP | disclosed |
| CN-107011190-A | A kind of 1,2 7-oxa-bicyclo[4.1.0 open loop prepares the new technology of β aminocyclohexanols | 湖南理工学院 | 2017-08-04 | — | — | CN | disclosed |
| CN-106477655-A | A kind of industrial sewage treating agent | 郑州天舜电子技术有限公司 | 2017-03-08 | — | — | CN | disclosed |
| US-9586899-B2 | Synthetic process for aminocyclohexyl ether compounds | CARDIOME PHARMA CORP. (CA) | 2017-03-07 | — | — | US | disclosed |
| US-9586899-B2 | Synthetic process for aminocyclohexyl ether compounds | CARDIOME PHARMA CORP. (CA) | 2017-03-07 | — | — | US | disclosed |
| US-9540377-B2 | 2,6,7,8 substituted purines as HDM2 inhibitors | MERCK SHARP & DOHME CORP. (US) | 2017-01-10 | — | — | US | disclosed |
| US-20160009694-A1 | CYCLOHEXANEDIAMINE COMPOUNDS AND METHODS FOR THEIR PREPARATION | ALEXION PHARMACEUTICALS, INC. | 2016-01-14 | — | — | US | disclosed |
| US-20160009694-A1 | CYCLOHEXANEDIAMINE COMPOUNDS AND METHODS FOR THEIR PREPARATION | ALEXION PHARMACEUTICALS, INC. | 2016-01-14 | — | — | US | disclosed |
| EP-1461315-B1 | CATALYTIC CARBONYLATION OF THREE AND FOUR MEMBERED HETEROCYCLES | CORNELL RES FOUNDATION INC (US) | 2009-07-29 | — | — | EP | disclosed |
| EP-1828099-A1 | SYNTHETIC PROCESS FOR AMINOCYCLOHEXYL ETHER COMPOUNDS | Cardimone Pharma Corporation (CA) | 2007-09-05 | — | — | EP | disclosed |
| WO-2007055180-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE TRANS-2-AMINOCYCLOHEXANOL AND DERIVATIVE THEREOF | TORAY FINE CHEMICALS CO., LTD. (JP) | 2007-05-18 | — | — | WO | disclosed |
| WO-2006088525-A1 | SYNTHETIC PROCESS FOR AMINOCYCLOHEXYL ETHER COMPOUNDS | CARDIOME PHARMA CORP. (CA) | 2006-08-24 | — | — | WO | disclosed |
| EP-1461315-A4 | CATALYTIC CARBONYLATION OF THREE AND FOUR MEMBERED HETEROCYCLES | CORNELL RES FOUNDATION INC (US) | 2005-06-01 | — | — | EP | disclosed |
| US-6852865-B2 | Catalytic carbonylation of three and four membered heterocycles | CORNELL RESEARCH FOUNDATION, INC. (US) | 2005-02-08 | — | — | US | disclosed |
| EP-1461315-A2 | CATALYTIC CARBONYLATION OF THREE AND FOUR MEMBERED HETEROCYCLES | CORNELL RESEARCH FOUNDATION, INC. (US) | 2004-09-29 | — | — | EP | disclosed |
| US-20040029875-A1 | Novel aminotriazolone compounds, method for preparing same and pharmaceutical compositions containing same | LES LABORATOIRES SERVIER (FR) | 2004-02-12 | — | — | US | disclosed |
| US-20030162961-A1 | Catalytic carbonylation of three and four membered heterocycles | CORNELL RESEARCH FOUNDATION, INC. | 2003-08-28 | — | — | US | disclosed |
| WO-2003050154-A2 | CATALYTIC CARBONYLATION OF THREE AND FOUR MEMBERED HETEROCYCLES | CORNELL RESEARCH FOUNDATION, INC. (US) | 2003-06-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160009694-A1 | CYCLOHEXANEDIAMINE COMPOUNDS AND METHODS FOR THEIR PREPARATION | SYK, BTK, LCK | LTA4H 968/4885FUCA1 1168/4885KDM1A 712/4885 |
| US-20040029875-A1 | Novel aminotriazolone compounds, method for preparing same and pharmaceutical compositions containing same | ADORA1, AASDHPPT, AADAT | LTA4H 649/4885FUCA1 3143/4885KDM1A 2252/4885 |
| US-20030162961-A1 | Catalytic carbonylation of three and four membered heterocycles | LOX, CA9, LPO | LTA4H 90/4885FUCA1 3834/4885KDM1A 247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.