Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1075938 | 0.88 | VCAM1 (0.53) | VCAM1KMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL1075935 | 0.88 | VCAM1 (0.53) | VCAM1KMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL1076592 | 0.80 | ALDH1A1 (0.54) | ACACBKMT2AALDH1A1CA12CA1 | |
| SCHEMBL1076812 | 0.79 | BDKRB1 (0.45) | ACACBKMT2AALDH1A1CA12CA1 | |
| SCHEMBL1076559 | 0.79 | KDM4E (0.54) | ACACBALDH1A1CA12CA1CA2 | |
| SCHEMBL28795052 | 0.79 | KDM4E (0.54) | ACACBALDH1A1CA12CA1CA2 | |
| SCHEMBL6560138 | 0.74 | HCAR3 (0.57) | KMT2AMEN1LMNA | |
| SCHEMBL21932200 | 0.74 | VCAM1 (0.56) | VCAM1KMT2AALDH1A1MEN1HPGD | |
| SCHEMBL14735881 | 0.74 | HCAR3 (0.57) | KMT2AMEN1LMNA | |
| SCHEMBL6560146 | 0.74 | HCAR3 (0.57) | KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009139373-A1 | AMIDE COMPOUND | アステラス製薬株式会社 (JP) | 2009-11-19 | — | — | WO | disclosed |