Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1716620 | 0.86 | POLB (0.53) | POLBCTDSP1ALOX5CYP2C19EPHX1 | |
| SCHEMBL13658246 | 0.83 | POLB (0.50) | POLBCTDSP1MTNR1AMTNR1BALOX5 | |
| SCHEMBL2120942 | 0.82 | CTSS (0.49) | POLBCTDSP1MTNR1AMTNR1BCYP2C19 | |
| SCHEMBL13385031 | 0.82 | CYP2C19 (0.49) | POLBMTNR1AMTNR1BCYP2C19EPHX1 | |
| SCHEMBL4441244 | 0.82 | TRPA1 (0.47) | POLBMTNR1AMTNR1BCYP2C19EPHX1 | |
| SCHEMBL5610660 | 0.81 | HPGD (0.47) | POLBMTNR1AMTNR1BALOX5CYP2C19 | |
| SCHEMBL8903384 | 0.81 | ALDH1A1 (0.46) | POLBMTNR1AMTNR1BCYP2C19EPHX1 | |
| SCHEMBL12824732 | 0.81 | HRH1 (0.52) | MTNR1AMTNR1BALOX5CYP2C19EPHX1 | |
| SCHEMBL7006798 | 0.80 | ALPI (0.50) | POLBCYP2C19EPHX1 | |
| SCHEMBL13684889 | 0.80 | KMT2A (0.55) | POLBCTDSP1LMNAALDH1A1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009134616-A2 | NOVEL INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2009-11-05 | — | — | WO | disclosed |