Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 4/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12213295 | 0.75 | LMNA (0.64) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL5502611 | 0.75 | LMNA (0.64) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL3096547 | 0.75 | LMNA (0.64) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL75867 | 0.75 | LMNA (0.64) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL3096537 | 0.75 | LMNA (0.64) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL22199538 | 0.74 | SLC6A2 (0.35) | SLC6A2SLC6A4SLC6A3KMT2A | |
| SCHEMBL8288165 | 0.74 | HTR2A (0.54) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13700642 | 0.73 | KDM4E (0.43) | LMNAKDM4EAOC3CYP2D6SLC6A4 | |
| SCHEMBL13700569 | 0.73 | KDM4E (0.43) | LMNAKDM4EAOC3CYP2D6SLC6A4 | |
| SCHEMBL17075907 | 0.73 | LMNA (0.61) | LMNAKDM4EL3MBTL1AOC3RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009137691-A2 | 1,3-DIOL SYNTHESIS VIA CONTROLLED, RADICAL-MEDIATED C-H FUNCTIONALIZATION | THE SCRIPPS RESEARCH INSTITUTE (US) | 2009-11-12 | — | — | WO | disclosed |