Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 2/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MLNR | O43193 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10326687 | 1.00 | CHRM5 (0.46) | CHRM5ADRA2CHTR1AHTR2AKCNH2 | |
| SCHEMBL10326492 | 1.00 | CHRM5 (0.46) | CHRM5ADRA2CHTR1AHTR2AKCNH2 | |
| SCHEMBL5219148 | 1.00 | CHRM5 (0.46) | CHRM5ADRA2CHTR1AHTR2AKCNH2 | |
| SCHEMBL1995891 | 1.00 | CHRM5 (0.46) | CHRM5ADRA2CHTR1AHTR2AKCNH2 | |
| SCHEMBL552106 | 1.00 | CHRM5 (0.46) | CHRM5ADRA2CHTR1AHTR2AKCNH2 | |
| SCHEMBL2387767 | 1.00 | CHRM5 (0.46) | CHRM5ADRA2CHTR1AHTR2AKCNH2 | |
| Hydrochloric Acid SCHEMBL1190644 | 0.98 | CHRM5 (0.45) | CHRM5ADRA2CHTR1AHTR2AKCNH2 | |
| SCHEMBL255277 | 0.98 | HTR1A (0.45) | CHRM5ADRA2CHTR1AHTR2AKCNH2 | |
| SCHEMBL16716869 | 0.98 | HTR1A (0.45) | CHRM5ADRA2CHTR1AHTR2AKCNH2 | |
| SCHEMBL488775 | 0.98 | HTR1A (0.45) | CHRM5ADRA2CHTR1AHTR2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090281346-A1 | METHOD FOR THE PRODUCTION OF CHIRAL AMINOCARBONYL COMPOUNDS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2009-11-12 | — | — | US | disclosed |
| US-20090281346-A1 | METHOD FOR THE PRODUCTION OF CHIRAL AMINOCARBONYL COMPOUNDS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2009-11-12 | — | — | US | disclosed |
| WO-2008009275-A1 | METHOD FOR THE PRODUCTION OF CHIRAL AMINOCARBONYL COMPOUNDS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2008-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090281346-A1 | METHOD FOR THE PRODUCTION OF CHIRAL AMINOCARBONYL COMPOUNDS | AOC3, AOC2, AOC1 | CHRM5 2899/4885ADRA2C 489/4885HTR1A 827/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.