Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 4/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1484949 | 1.00 | POLB (0.51) | POLBCHRNB2CHRNA4HTR6CHRNB4 | |
| SCHEMBL1484948 | 1.00 | POLB (0.51) | POLBCHRNB2CHRNA4HTR6CHRNB4 | |
| SCHEMBL30931485 | 1.00 | POLB (0.51) | POLBCHRNB2CHRNA4HTR6CHRNB4 | |
| SCHEMBL2109274 | 0.95 | POLB (0.58) | POLBCHRNB2CHRNA4HTR6LTA4H | |
| SCHEMBL25281271 | 0.94 | POLB (0.57) | POLBCHRNB2CHRNA4LTA4H | |
| SCHEMBL818603 | 0.79 | LTA4H (0.43) | LTA4H | |
| SCHEMBL3161248 | 0.76 | CHRNB2 (0.46) | POLBCHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL27946219 | 0.76 | HPGD (0.47) | POLBLTA4H | |
| SCHEMBL7356653 | 0.75 | CYP2D6 (0.43) | — | |
| SCHEMBL15358977 | 0.75 | DDB1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090281346-A1 | METHOD FOR THE PRODUCTION OF CHIRAL AMINOCARBONYL COMPOUNDS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2009-11-12 | — | — | US | disclosed |
| US-20090281346-A1 | METHOD FOR THE PRODUCTION OF CHIRAL AMINOCARBONYL COMPOUNDS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2009-11-12 | — | — | US | disclosed |
| EP-2103619-A1 | IMIDAZOTHIAZOLE DERIVATIVES | Daiichi Sankyo Company, Limited (JP) | 2009-09-23 | — | — | EP | disclosed |
| WO-2008009275-A1 | METHOD FOR THE PRODUCTION OF CHIRAL AMINOCARBONYL COMPOUNDS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2008-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090281346-A1 | METHOD FOR THE PRODUCTION OF CHIRAL AMINOCARBONYL COMPOUNDS | AOC3, AOC2, AOC1 | POLB 2136/4885CHRNB2 2594/4885CHRNA4 3265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.