Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL979263 | 0.78 | HTR3A (0.38) | ALDH1A1MAPTHTTNPC1S1PR4 | |
| SCHEMBL980682 | 0.73 | PDE1A (0.43) | KMT2ANPBWR1MCHR1GAA | |
| SCHEMBL1751014 | 0.69 | NPBWR1 (0.56) | ALDH1A1MAPTHTTNPC1S1PR4 | |
| SCHEMBL980667 | 0.69 | CYP1A2 (0.40) | ALDH1A1NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL1550906 | 0.67 | NPBWR1 (0.59) | HTTKMT2ASMN1; SMN2NPBWR1MCHR1 | |
| SCHEMBL9464494 | 0.65 | IDH1 (0.44) | IDH1NPC1RAB9A | |
| SCHEMBL1750445 | 0.64 | NPBWR1 (0.44) | ALDH1A1MAPTHTTNPC1S1PR4 | |
| SCHEMBL4810016 | 0.63 | TUBB4A (0.47) | ALDH1A1MAPTHTTNPC1RAB9A | |
| SCHEMBL15232194 | 0.61 | KMT2A (0.43) | MAPTKMT2ANPBWR1MCHR1LMNA | |
| SCHEMBL23414968 | 0.61 | ALPL (0.49) | ALDH1A1MAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2123264-A1 | Heterocyclic derivatives as abnormal cannabidiols agents for lowering intraocular pressure | Allergan, Inc. (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2007127711-A2 | ABNORMAL CANNABIDIOLS AS AGENTS FOR LOWERING INTRAOCULAR PRESSURE | ALLERGAN, INC. (US) | 2007-11-08 | — | — | WO | disclosed |