Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.46 |
| ▸ | F12 | P00748 | 3/20 | 0.46 |
| ▸ | MGAM | O43451 | 2/20 | 0.46 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | SI | P14410 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2095767 | 0.83 | KDM4E (0.59) | SMN1; SMN2LMNAKDM4ETSHRRECQL | |
| SCHEMBL2091203 | 0.78 | FGFR1 (0.56) | SMN1; SMN2LMNAKDM4ETSHRRECQL | |
| SCHEMBL2096963 | 0.77 | MGAM (0.55) | SMN1; SMN2LMNAKDM4ENPSR1MAPT | |
| SCHEMBL2092784 | 0.77 | SMN1; SMN2 (0.59) | SMN1; SMN2LMNAKDM4ETSHRRECQL | |
| SCHEMBL21022145 | 0.76 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAKDM4ETSHRRECQL | |
| SCHEMBL28678482 | 0.74 | HDAC3 (0.55) | SMN1; SMN2LMNAKDM4ETSHRRECQL | |
| SCHEMBL2089555 | 0.74 | KCNMA1 (0.50) | SMN1; SMN2LMNAKDM4ETSHRRECQL | |
| SCHEMBL10103354 | 0.72 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNAKDM4ETSHRRECQL | |
| SCHEMBL19848332 | 0.72 | ALDH1A1 (0.56) | SMN1; SMN2LMNAKDM4ETSHRNPSR1 | |
| SCHEMBL19848194 | 0.72 | NPC1 (0.60) | SMN1; SMN2LMNAKDM4ETSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2123264-A1 | Heterocyclic derivatives as abnormal cannabidiols agents for lowering intraocular pressure | Allergan, Inc. (US) | 2009-11-25 | — | — | EP | disclosed |