Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | RCE1 | Q9Y256 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 5/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13620481 | 0.76 | SMN1; SMN2 (0.53) | SMN1; SMN2NPC1RAB9ATP53LMNA | |
| SCHEMBL24060749 | 0.75 | KCNMA1 (0.53) | SMN1; SMN2RAB9ALMNAALDH1A1KDM4E | |
| SCHEMBL4209963 | 0.74 | KCNMA1 (0.64) | SMN1; SMN2RAB9ALMNAALDH1A1MAPT | |
| SCHEMBL2096963 | 0.73 | MGAM (0.55) | SMN1; SMN2NPC1RAB9ATP53LMNA | |
| SCHEMBL21021424 | 0.71 | KCNMA1 (0.40) | SMN1; SMN2NPC1RAB9ATP53ALDH1A1 | |
| SCHEMBL2095767 | 0.70 | KDM4E (0.59) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL24776900 | 0.70 | SMN1; SMN2 (0.48) | SMN1; SMN2RAB9ALMNAALDH1A1MAPT | |
| SCHEMBL16314217 | 0.69 | SMN1; SMN2 (0.47) | SMN1; SMN2RAB9ALMNAALDH1A1MAPT | |
| SCHEMBL21467623 | 0.68 | RAB9A (0.46) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL463197 | 0.68 | MAPT (0.70) | SMN1; SMN2NPC1RAB9ATP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283459-B1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2019-05-22 | — | — | EP | disclosed |