Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 12/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 12/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29686939 | 0.74 | RAB9A (0.51) | HCRTR1HCRTR2 | |
| SCHEMBL4263055 | 0.74 | RAB9A (0.51) | HCRTR1HCRTR2 | |
| SCHEMBL22235655 | 0.72 | TDP1 (0.57) | HCRTR1HCRTR2MEN1KMT2APOLB | |
| SCHEMBL17859342 | 0.69 | HCRTR2 (0.51) | HCRTR1HCRTR2POLBLMNAGPBAR1 | |
| SCHEMBL13622324 | 0.69 | NNMT (0.33) | MEN1KMT2AMAPK1 | |
| SCHEMBL28314178 | 0.69 | HCRTR2 (0.49) | HCRTR1HCRTR2POLBLMNAGPBAR1 | |
| SCHEMBL13622908 | 0.69 | LMNA (0.41) | MEN1KMT2ALMNA | |
| SCHEMBL456915 | 0.68 | NAPRT (0.50) | HCRTR1HCRTR2MEN1KMT2ALMNA | |
| SCHEMBL30919007 | 0.68 | NAPRT (0.50) | HCRTR1HCRTR2MEN1KMT2ALMNA | |
| SCHEMBL19599247 | 0.67 | HCRTR2 (0.52) | HCRTR1HCRTR2MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009138712-A2 | CHEMICAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2009-11-19 | — | — | WO | disclosed |