Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 5/20 | 0.39 |
| ▸ | PKM | P14618 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13622393 | 0.80 | GSK3B (0.39) | LMNAHPGDGSK3B | |
| SCHEMBL13622389 | 0.80 | SMN1; SMN2 (0.37) | LMNARAB9ANPC1KMT2AMAPT | |
| SCHEMBL13622603 | 0.75 | TUBB4A (0.44) | LMNARAB9ANPC1KMT2AMAPT | |
| SCHEMBL13256628 | 0.73 | ALDH1A1 (0.35) | — | |
| SCHEMBL13622324 | 0.71 | NNMT (0.33) | KMT2AL3MBTL1KDM4EMEN1 | |
| SCHEMBL7702480 | 0.70 | CES2 (0.50) | LMNARAB9ANPC1KMT2AMAPT | |
| SCHEMBL13256629 | 0.69 | ALDH1A1 (0.32) | — | |
| SCHEMBL13622605 | 0.69 | HCRTR1 (0.37) | LMNAKMT2AMEN1 | |
| SCHEMBL13622361 | 0.69 | ALDH1A1 (0.39) | RAB9ANPC1KMT2AMAPTHPGD | |
| SCHEMBL13622400 | 0.67 | ATAD2 (0.34) | NPC1KMT2AHPGDL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009138712-A2 | CHEMICAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2009-11-19 | — | — | WO | disclosed |