SCHEMBL13623387

SCHEMBL13623387

O=C(NS(=O)(=O)c1ccc(C(F)(F)F)cc1)c1ccc(C(F)(F)F)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FLT1 P17948 6/20 0.64
FLT4 P35916 6/20 0.64
KDR P35968 6/20 0.64
ALKBH2 Q6NS38 1/20 0.60
ALKBH5 Q6P6C2 1/20 0.60
ALKBH3 Q96Q83 1/20 0.60
FTO Q9C0B1 1/20 0.60
PTGS2 P35354 4/20 0.59
MMP1 P03956 2/20 0.58
PTGS1 P23219 2/20 0.55
MEN1 O00255 1/20 0.54
LMNA P02545 1/20 0.54
KMT2A Q03164 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
PTPN1 P18031 1/20 0.53
TRPV4 Q9HBA0 1/20 0.52
CES2 O00748 1/20 0.52
CES1 P23141 1/20 0.52
BCL2L1 Q07817 1/20 0.51
MCL1 Q07820 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29109027 0.92 PTGS2 (0.68) FLT1FLT4KDRALKBH2ALKBH5
SCHEMBL19248164 0.92 PTPN1 (0.64) FLT1FLT4KDRALKBH2ALKBH5
SCHEMBL12458729 0.89 PTPN1 (0.58) FLT1FLT4KDRALKBH2ALKBH5
SCHEMBL12459443 0.88 FLT1 (0.51) FLT1FLT4KDRALKBH2ALKBH5
SCHEMBL28956653 0.88 TRPV4 (0.53) FLT1FLT4KDRALKBH2ALKBH5
SCHEMBL24713395 0.85 MMP1 (0.57) FLT1FLT4KDRALKBH2ALKBH5
SCHEMBL12459304 0.85 GAA (0.58) MEN1LMNAKMT2ATRPV4
SCHEMBL12459442 0.84 MMP1 (0.53) FLT1FLT4KDRALKBH2ALKBH5
SCHEMBL1951647 0.84 MMP1 (0.55) FLT1FLT4KDRALKBH2ALKBH5
SCHEMBL19630963 0.82 DHFR (0.61) FLT1FLT4KDRALKBH2ALKBH5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7618683-B2 Ink composition, inkjet recording method, printed material, process for producing lithographic printing plate, and lithographic printing plate FUJIFILM CORPORATION (JP) 2009-11-17 US disclosed
EP-1808466-A1 Ink composition, inkjet recording method, printed material, process for producing lithographic printing plate, and lithographic printing plate Fujifilm Corporation (JP) 2007-07-18 EP disclosed
US-20070160815-A1 Ink composition, inkjet recording method, printed material, process for producing lithographic printing plate, and lithographic printing plate FUJIFILM CORPORATION (JP) 2007-07-12 US disclosed
US-20070160815-A1 Ink composition, inkjet recording method, printed material, process for producing lithographic printing plate, and lithographic printing plate FUJIFILM CORPORATION (JP) 2007-07-12 US disclosed