Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 7/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 6/20 | 0.42 |
| ▸ | MGLL | Q99685 | 2/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13624137 | 0.84 | NR3C1 (0.59) | NR3C1HPGDMAPK10MAPK8MGLL | |
| SCHEMBL13623929 | 0.84 | NR3C1 (0.59) | NR3C1HPGDMAPK10MAPK8MGLL | |
| SCHEMBL3144673 | 0.76 | NR3C1 (0.80) | NR3C1PGR | |
| SCHEMBL13624663 | 0.74 | MAPK10 (0.49) | NR3C1HPGDMAPK10MAPK8MGLL | |
| SCHEMBL13623928 | 0.73 | MAPK10 (0.48) | NR3C1HPGDMAPK10MAPK8PGR | |
| SCHEMBL13624666 | 0.71 | NR3C1 (0.49) | NR3C1MAPK10MAPK8HPGDS | |
| SCHEMBL13624667 | 0.71 | MAPK10 (0.51) | NR3C1MAPK10MAPK8PGR | |
| SCHEMBL13624133 | 0.69 | MAPK10 (0.54) | MAPK10MAPK8HPGDS | |
| SCHEMBL13623919 | 0.68 | MAPK10 (0.67) | MAPK10MAPK8 | |
| SCHEMBL13045122 | 0.67 | MAPK8 (0.65) | NR3C1HPGDMAPK10MAPK8PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009142569-A1 | PHENYL OR PYRIDINYL SUBSTITUTED INDAZOLES DERIVATIVES | ASTRAZENECA AB (SE) | 2009-11-26 | — | — | WO | disclosed |