Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GPR3 | P46089 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13624143 | 0.81 | NQO1 (0.45) | MRGPRX4ALDH1A1KDM4ECYP3A4HPGD | |
| SCHEMBL15496973 | 0.80 | CYP2C9 (0.44) | CYP2C9CYP1A2ALDH1A1CYP2C19CYP17A1 | |
| SCHEMBL2493524 | 0.79 | TRPV4 (0.53) | CYP2C9CYP1A2ALDH1A1CYP2C19CYP17A1 | |
| SCHEMBL13624065 | 0.79 | MAPK1 (0.41) | MRGPRX4ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL799917 | 0.79 | CA1 (0.58) | CYP2C9CYP1A2ALDH1A1CYP2C19KDM4E | |
| SCHEMBL31525792 | 0.79 | CA1 (0.58) | CYP2C9CYP1A2ALDH1A1CYP2C19KDM4E | |
| SCHEMBL13624074 | 0.78 | LMNA (0.42) | ALDH1A1GPR3CYP3A4HPGDLMNA | |
| SCHEMBL3923642 | 0.78 | CYP2C9 (0.51) | CYP2C9CYP1A2ALDH1A1CYP2C19CYP17A1 | |
| SCHEMBL23977887 | 0.77 | CYP2C9 (0.50) | CYP2C9CYP1A2ALDH1A1CYP2C19CYP17A1 | |
| SCHEMBL22140426 | 0.76 | MAOB (0.43) | MRGPRX4ALDH1A1KDM4ECYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090291945-A1 | CYSTEINE PROTEASE INHIBITORS | TEIJIN PHARMA LIMITED (JP) | 2009-11-26 | — | — | US | disclosed |
| US-20090291945-A1 | CYSTEINE PROTEASE INHIBITORS | TEIJIN PHARMA LIMITED (JP) | 2009-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090291945-A1 | CYSTEINE PROTEASE INHIBITORS | CTSE, SPINT2, CTSF | MRGPRX4 625/4885CYP2C9 968/4885CYP1A2 3323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.