Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 16/20 | 0.53 |
| ▸ | CTSL | P07711 | 16/20 | 0.53 |
| ▸ | CTSB | P07858 | 7/20 | 0.48 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13624301 | 0.90 | CTSK (0.64) | CTSKCTSLCTSBCTSS | |
| SCHEMBL13624431 | 0.88 | CTSL (0.48) | CTSKCTSLCTSBCTSS | |
| SCHEMBL13624313 | 0.82 | CTSL (0.48) | CTSKCTSLCTSBCTSS | |
| SCHEMBL13624385 | 0.81 | CTSL (0.48) | CTSKCTSLCTSBCTSS | |
| SCHEMBL13624437 | 0.80 | CTSL (0.47) | CTSKCTSLCTSBCTSS | |
| SCHEMBL13624438 | 0.80 | CTSL (0.47) | CTSKCTSLCTSBCTSS | |
| SCHEMBL13624435 | 0.80 | CTSL (0.46) | CTSKCTSLCTSBCTSS | |
| SCHEMBL13624434 | 0.79 | CTSK (0.41) | CTSKCTSLCTSBCTSS | |
| SCHEMBL13624314 | 0.76 | CTSL (0.45) | CTSKCTSLCTSBCTSS | |
| SCHEMBL13624447 | 0.75 | CTSL (0.47) | CTSKCTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090291945-A1 | CYSTEINE PROTEASE INHIBITORS | TEIJIN PHARMA LIMITED (JP) | 2009-11-26 | — | — | US | disclosed |
| US-20090291945-A1 | CYSTEINE PROTEASE INHIBITORS | TEIJIN PHARMA LIMITED (JP) | 2009-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090291945-A1 | CYSTEINE PROTEASE INHIBITORS | CTSE, SPINT2, CTSF | CTSK 15/4885CTSL 24/4885CTSB 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.