SCHEMBL13624500

SCHEMBL13624500

CC(OC(=O)COCC(=O)OC(C)C(=O)O)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 1/20 0.38
MMP2 P08253 1/20 0.38
MMP3 P08254 1/20 0.38
MMP9 P14780 1/20 0.38
MMP13 P45452 1/20 0.38
TP53 P04637 1/20 0.33
MAPT P10636 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
TDP1 Q9NUW8 2/20 0.32
TSHR P16473 1/20 0.31
CYP1A2 P05177 2/20 0.31
GAA P10253 1/20 0.31
CYP2C9 P11712 1/20 0.31
PKM P14618 1/20 0.31
CYP2C19 P33261 1/20 0.31
KMT2A Q03164 1/20 0.31
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
HSD17B10 Q99714 1/20 0.30
RNPEP Q9H4A4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15095099 0.84 MMP1 (0.36) MMP1MMP2MMP3MMP9MMP13
SCHEMBL2608669 0.80 LMNA (0.40) MMP1MMP2MMP3MMP9MMP13
SCHEMBL7110445 0.80 LMNA (0.40) MMP1MMP2MMP3MMP9MMP13
SCHEMBL18232155 0.79 ADORA3 (0.33) KMT2A
SCHEMBL6381127 0.79 MMP1 (0.37) MMP1MMP2MMP3MMP9MMP13
SCHEMBL4263079 0.79 TP53 (0.39) MMP1MMP2MMP3MMP9MMP13
SCHEMBL6381118 0.79 MMP1 (0.33) MMP1MMP2MMP3MMP9MMP13
SCHEMBL9422960 0.78 TSHR (0.47) MAPTL3MBTL1TSHRCYP1A2CYP2C9
SCHEMBL682065 0.78 TDP1 (0.33) TDP1
SCHEMBL682062 0.78 MMP1 (0.39) MMP1MMP2MMP3MMP9MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130035402-A1 BIOABSORBABLE POLYESTERAMIDES AND USES THEREOF BEZWADA BIOMEDICAL, LLC (US) 2013-02-07 US disclosed
US-20130035402-A1 BIOABSORBABLE POLYESTERAMIDES AND USES THEREOF BEZWADA BIOMEDICAL, LLC (US) 2013-02-07 US disclosed
US-8309132-B2 Bioabsorbable polyesteramides and uses thereof BEZWADA BIOMEDICAL, LLC (US) 2012-11-13 US disclosed
US-8309132-B2 Bioabsorbable polyesteramides and uses thereof BEZWADA BIOMEDICAL, LLC (US) 2012-11-13 US disclosed
US-20090285896-A1 BIOABSORBABLE POLYESTERAMIDES AND USES THEREOF BEZWADA BIOMEDICAL, LLC (US) 2009-11-19 US disclosed
US-20090285896-A1 BIOABSORBABLE POLYESTERAMIDES AND USES THEREOF BEZWADA BIOMEDICAL, LLC (US) 2009-11-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090285896-A1 BIOABSORBABLE POLYESTERAMIDES AND USES THEREOF PAICS, UROD, PUF60 MMP1 1315/4885MMP2 1587/4885MMP3 3616/4885
US-20130035402-A1 BIOABSORBABLE POLYESTERAMIDES AND USES THEREOF PAICS, UROD, PUF60 MMP1 1315/4885MMP2 1587/4885MMP3 3616/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.