Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KDM6B | O15054 | 1/20 | 0.34 |
| ▸ | KDM5C | P41229 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2608669 | 1.00 | LMNA (0.40) | LMNAMMP1MMP2MMP3MMP9 | |
| Acetic Acid SCHEMBL22769870 | 0.95 | LMNA (0.38) | LMNAMMP1MMP2MMP3MMP9 | |
| SCHEMBL935213 | 0.93 | EGLN1 (0.45) | LMNAMMP1MMP2MMP3MMP9 | |
| SCHEMBL9817250 | 0.93 | LMNA (0.50) | LMNAMMP1MMP2MMP3MMP9 | |
| SCHEMBL18218913 | 0.91 | ALDH1A1 (0.43) | LMNAMMP1MMP2MMP3MMP9 | |
| SCHEMBL19107033 | 0.89 | LMNA (0.34) | LMNAMMP1MMP2MMP3MMP9 | |
| SCHEMBL18651161 | 0.88 | ALDH1A1 (0.48) | LMNAMMP1MMP2MMP3MMP9 | |
| SCHEMBL4622341 | 0.88 | ALDH1A1 (0.48) | LMNAMMP1MMP2MMP3MMP9 | |
| SCHEMBL2520414 | 0.88 | LMNA (0.36) | LMNAMMP1MMP2MMP3MMP9 | |
| SCHEMBL2353376 | 0.87 | CA1 (0.43) | LMNAMMP1MMP2MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030078339-A1 | Degradable cross-linking agents and cross-linked network polymers formed therewith | ACCESS PHARMACEUTICALS, INC. | 2003-04-24 | — | — | US | disclosed |
| US-6521431-B1 | Cosmetic and drug-time release agents; hazardous waste remediation, metal chelation, wound healing agents | ACCESS PHARMACEUTICALS, INC. | 2003-02-18 | — | — | US | disclosed |