Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 2/20 | 0.47 |
| ▸ | ALPI | P09923 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.45 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13624582 | 0.80 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL5470345 | 0.76 | RAB9A (0.58) | KDM4EALDH1A1HPGDHSD17B10RAB9A | |
| SCHEMBL15842341 | 0.76 | ALPL (0.74) | ALPLALPIKDM4EALDH1A1HPGD | |
| SCHEMBL16695703 | 0.76 | KDM4E (0.54) | ALPLALPIKDM4EALDH1A1HPGD | |
| SCHEMBL4657752 | 0.73 | ALPL (0.41) | ALPLALPIKDM4EALDH1A1HPGD | |
| SCHEMBL11397024 | 0.72 | KDM4E (0.60) | ALPLALPIKDM4EALDH1A1HPGD | |
| SCHEMBL11750821 | 0.69 | CA1 (0.61) | ALPLALPIKDM4EALDH1A1HPGD | |
| SCHEMBL13624584 | 0.68 | PDE9A (0.46) | KDM4EGAA | |
| SCHEMBL17284920 | 0.68 | KMT2A (0.68) | KDM4EALDH1A1HPGDHSD17B10RAB9A | |
| SCHEMBL2284104 | 0.68 | KDM4E (0.57) | KDM4EALDH1A1HPGDHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622582-B2 | Derivatives of 1-phenyl-benzofuro[3,2]pyridin-2(1H)-one | TIBOTEC BVBA (BE) | 2009-11-24 | — | — | US | disclosed |
| US-7622582-B2 | Derivatives of 1-phenyl-benzofuro[3,2]pyridin-2(1H)-one | TIBOTEC BVBA (BE) | 2009-11-24 | — | — | US | disclosed |
| US-20070213320-A1 | 4-SUBSTITUTED-1,5-DIHYDRO-PYRIDO[3,2-B]INDOL-2-ONES | TIBOTEC BVBA (BE) | 2007-09-13 | — | — | US | disclosed |
| US-20070213320-A1 | 4-SUBSTITUTED-1,5-DIHYDRO-PYRIDO[3,2-B]INDOL-2-ONES | TIBOTEC BVBA (BE) | 2007-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213320-A1 | 4-SUBSTITUTED-1,5-DIHYDRO-PYRIDO[3,2-B]INDOL-2-ONES | NR2C2, CYP4B1, OXER1 | ALPL 4679/4885ALPI 4752/4885KDM4E 3819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.