Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.54 |
| ▸ | PIM1 | P11309 | 3/20 | 0.46 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 2/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CDK4 | P11802 | 1/20 | 0.45 |
| ▸ | CCND1 | P24385 | 1/20 | 0.45 |
| ▸ | KLK7 | P49862 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12667306 | 0.82 | KDM4E (0.47) | KDM4EPIM1ALDH1A1RXFP1HPGD | |
| SCHEMBL436095 | 0.82 | KDM4E (0.63) | KDM4ESTING1ALDH1A1RXFP1HPGD | |
| SCHEMBL982356 | 0.80 | KDM4E (0.53) | KDM4EALDH1A1RXFP1HPGDMEN1 | |
| SCHEMBL14916740 | 0.80 | PDE9A (0.65) | KDM4EPIM1ALDH1A1HPGDMEN1 | |
| SCHEMBL4741686 | 0.79 | GRIN2D (0.51) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL5618530 | 0.79 | MAPK1 (0.59) | KDM4EPIM1ALDH1A1HPGDMEN1 | |
| SCHEMBL13624588 | 0.76 | ALPL (0.47) | KDM4EPIM1ALDH1A1HPGDMEN1 | |
| SCHEMBL7915031 | 0.75 | PDE9A (0.64) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL23885417 | 0.75 | NSD2 (0.48) | KDM4EALDH1A1RXFP1HPGDMEN1 | |
| SCHEMBL30254651 | 0.75 | NSD2 (0.48) | KDM4EALDH1A1RXFP1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9708332-B2 | Respiratory syncytial virus inhibitors | MEDIVIR AB (SE) | 2017-07-18 | — | — | US | disclosed |
| US-9708332-B2 | Respiratory syncytial virus inhibitors | MEDIVIR AB (SE) | 2017-07-18 | — | — | US | disclosed |
| WO-2015065338-A1 | QUINAZOLINE BASED RESPIRATORY SYNCYTIAL VIRUS INHIBITORS | MEDIVIR AB (SE) | 2015-05-07 | — | — | WO | disclosed |