Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 18/20 | 0.51 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4157194 | 0.86 | HTR6 (0.56) | HTR6 | |
| SCHEMBL13624636 | 0.72 | TP53 (0.56) | HTR6 | |
| SCHEMBL14142098 | 0.71 | MEN1 (0.43) | BRD3ACHE | |
| SCHEMBL12093313 | 0.70 | HTR6 (0.70) | HTR6 | |
| SCHEMBL836107 | 0.68 | HTR6 (1.00) | HTR6 | |
| SCHEMBL10747917 | 0.67 | HTR6 (0.66) | HTR6 | |
| SCHEMBL8033752 | 0.67 | HTR6 (0.61) | HTR6 | |
| SCHEMBL16848484 | 0.66 | ACHE (0.38) | HTR6BRD3ACHE | |
| SCHEMBL8021900 | 0.66 | HTR6 (0.68) | HTR6 | |
| SCHEMBL6517647 | 0.66 | HTR6 (1.00) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622494-B2 | Chemical compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2009-11-24 | — | — | US | disclosed |
| US-20090170923-A1 | HCV INHIBITORS | SMITHKLINE BEECHAM CORPORATION | 2009-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170923-A1 | HCV INHIBITORS | HAVCR2, MAVS, EIF2AK2 | HTR6 4552/4885BRD3 4059/4885ACHE 3889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.