Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 6/20 | 0.55 |
| ▸ | GNPAT | O15228 | 2/20 | 0.54 |
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.54 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.42 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.42 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | NPY4R | P50391 | 5/20 | 0.41 |
| ▸ | NPY1R | P25929 | 3/20 | 0.41 |
| ▸ | NPY2R | P49146 | 3/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.41 |
| ▸ | ALB | P02768 | 2/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30248962 | 1.00 | FOLH1 (0.55) | FOLH1GNPATSIRT5RIMKLANAALAD2 | |
| SCHEMBL29655002 | 0.94 | GNPAT (0.53) | FOLH1GNPATSIRT5SIRT6SIRT1 | |
| SCHEMBL31094973 | 0.94 | GNPAT (0.53) | FOLH1GNPATSIRT5SIRT6SIRT1 | |
| SCHEMBL1718474 | 0.94 | GNPAT (0.53) | FOLH1GNPATSIRT5SIRT6SIRT1 | |
| SCHEMBL29454444 | 0.94 | GNPAT (0.53) | FOLH1GNPATSIRT5SIRT6SIRT1 | |
| SCHEMBL13701342 | 0.93 | SIRT5 (0.57) | FOLH1GNPATSIRT5SIRT6SIRT1 | |
| SCHEMBL13701341 | 0.93 | SIRT5 (0.63) | FOLH1GNPATSIRT5SIRT6SIRT1 | |
| SCHEMBL31157736 | 0.90 | NPY4R (0.48) | FOLH1GNPATSIRT5NPY4RNPY1R | |
| SCHEMBL31157664 | 0.90 | NPY4R (0.48) | FOLH1GNPATSIRT5NPY4RNPY1R | |
| SCHEMBL1705359 | 0.90 | GNPAT (0.50) | FOLH1GNPATSIRT5SIRT6SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622446-B2 | Polypeptides, derivatives and uses thereof | THE OPEN UNIVERSITY (GB) | 2009-11-24 | — | — | US | disclosed |