Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNPAT | O15228 | 2/20 | 0.53 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.50 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPY4R | P50391 | 10/20 | 0.43 |
| ▸ | NPY1R | P25929 | 7/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.43 |
| ▸ | NPY2R | P49146 | 3/20 | 0.43 |
| ▸ | ALB | P02768 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1718474 | 1.00 | GNPAT (0.53) | GNPATSIRT5SIRT6SIRT1FOLH1 | |
| SCHEMBL31094973 | 1.00 | GNPAT (0.53) | GNPATSIRT5SIRT6SIRT1FOLH1 | |
| SCHEMBL29655002 | 1.00 | GNPAT (0.53) | GNPATSIRT5SIRT6SIRT1FOLH1 | |
| SCHEMBL1705359 | 0.96 | GNPAT (0.50) | GNPATSIRT5SIRT6SIRT1FOLH1 | |
| SCHEMBL446929 | 0.94 | FOLH1 (0.49) | GNPATSIRT5SIRT6SIRT1FOLH1 | |
| SCHEMBL30526285 | 0.94 | FOLH1 (0.49) | GNPATSIRT5SIRT6SIRT1FOLH1 | |
| SCHEMBL468901 | 0.94 | FOLH1 (0.49) | GNPATSIRT5SIRT6SIRT1FOLH1 | |
| SCHEMBL6026003 | 0.94 | FOLH1 (0.49) | GNPATSIRT5SIRT6SIRT1FOLH1 | |
| SCHEMBL29396582 | 0.94 | SIRT6 (0.56) | GNPATSIRT5SIRT6SIRT1FOLH1 | |
| SCHEMBL29397145 | 0.94 | SIRT6 (0.56) | GNPATSIRT5SIRT6SIRT1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114605578-A | Preparation method and application of membrane-permeable brush-shaped polymer entering cells through pore-formation-mediated direct translocation mode | 南开大学 | 2022-06-10 | — | — | CN | claimed |
| US-20220227813-A1 | Ras INHIBITORY PEPTIDE | ICHIMARU PHARCOS CO., LTD. (JP) | 2022-07-21 | — | — | US | disclosed |
| CN-114605578-A | Preparation method and application of membrane-permeable brush-shaped polymer entering cells through pore-formation-mediated direct translocation mode | 南开大学 | 2022-06-10 | — | — | CN | disclosed |
| EP-3970801-A1 | RAS INHIBITORY PEPTIDE | Ichimaru Pharcos Co., Ltd. (JP) | 2022-03-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220227813-A1 | Ras INHIBITORY PEPTIDE | RSU1, RASGRP1, RASSF5 | GNPAT 3330/4885SIRT5 4255/4885SIRT6 4270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.