Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10126869 | 1.00 | RAB9A (0.36) | RAB9ACYP3A4CYP1A2CYP2D6TSHR | |
| SCHEMBL12018913 | 1.00 | RAB9A (0.36) | RAB9ACYP3A4CYP1A2CYP2D6TSHR | |
| SCHEMBL12018912 | 0.90 | OPRD1 (0.37) | RAB9ACYP3A4CYP1A2CYP2D6TSHR | |
| SCHEMBL10126868 | 0.90 | OPRD1 (0.37) | RAB9ACYP3A4CYP1A2CYP2D6TSHR | |
| SCHEMBL947664 | 0.84 | KDM4E (0.40) | RAB9ACYP3A4CYP1A2CYP2D6TSHR | |
| SCHEMBL980703 | 0.84 | HTR1A (0.40) | RAB9ACYP3A4CYP1A2CYP2D6TSHR | |
| SCHEMBL980704 | 0.84 | HTR1A (0.40) | RAB9ACYP3A4CYP1A2CYP2D6TSHR | |
| SCHEMBL1950445 | 0.83 | MEN1 (0.40) | HSD17B10MEN1ALDH1A1KMT2ACHRM4 | |
| SCHEMBL10126865 | 0.81 | MEN1 (0.40) | MEN1KMT2ACHRM4 | |
| SCHEMBL1357343 | 0.80 | ALDH1A1 (0.43) | RAB9ACYP3A4CYP1A2TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140447-A1 | IMMUNOMODULATION BY IAP INHIBITORS | NOVARTIS AG (CH) | 2009-11-19 | — | — | WO | disclosed |
| EP-2065368-A1 | Inhibitors of IAP | Novartis Ag (CH) | 2009-06-03 | — | — | EP | disclosed |