Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13953597 | 0.86 | ALOX5 (0.40) | ALOX5MEN1KMT2ASMN1; SMN2CYP2D6 | |
| SCHEMBL13552165 | 0.83 | ALDH1A1 (0.38) | ALOX5MEN1KMT2ASMN1; SMN2CNR1 | |
| SCHEMBL15241497 | 0.83 | ALOX5 (0.40) | ALOX5MEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL15436371 | 0.83 | ALOX5 (0.41) | ALOX5MEN1KMT2ATRPM8SMN1; SMN2 | |
| SCHEMBL15436313 | 0.82 | CYP2C19 (0.40) | ALOX5MEN1KMT2ASMN1; SMN2CNR1 | |
| SCHEMBL13538362 | 0.82 | CYP2C19 (0.40) | ALOX5MEN1KMT2ASMN1; SMN2CNR1 | |
| SCHEMBL16791662 | 0.82 | DPP4 (0.37) | ALOX5TRPM8ALDH1A1LMNA | |
| SCHEMBL15241454 | 0.81 | ALOX5 (0.38) | ALOX5MEN1KMT2ASMN1; SMN2CNR1 | |
| SCHEMBL13624935 | 0.81 | ALOX5 (0.38) | ALOX5MEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL17120320 | 0.77 | ALOX5 (0.38) | ALOX5MEN1KMT2ASMN1; SMN2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009134400-A1 | CYCLIC INHIBITORS OF 11BETA-HYDROXYSTEROID DEHYDROGENASE 1 | VITAE PHARMACEUTICALS, INC. (US) | 2009-11-05 | — | — | WO | disclosed |