Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13538362 | 1.00 | CYP2C19 (0.40) | CYP2C19ALOX5MEN1KMT2APMP22 | |
| SCHEMBL13538484 | 0.91 | ALOX5 (0.37) | CYP2C19ALOX5PMP22L3MBTL1 | |
| SCHEMBL13953564 | 0.86 | TRPM8 (0.41) | CYP2C19ALDH1A1 | |
| SCHEMBL13953597 | 0.85 | ALOX5 (0.40) | ALOX5MEN1KMT2APMP22CNR1 | |
| SCHEMBL13552165 | 0.84 | ALDH1A1 (0.38) | ALOX5MEN1KMT2APMP22CNR1 | |
| SCHEMBL13624935 | 0.84 | ALOX5 (0.38) | ALOX5MEN1KMT2APMP22CNR1 | |
| SCHEMBL15241497 | 0.84 | ALOX5 (0.40) | ALOX5MEN1KMT2APMP22CNR1 | |
| SCHEMBL15241454 | 0.82 | ALOX5 (0.38) | ALOX5MEN1KMT2APMP22CNR1 | |
| SCHEMBL13624952 | 0.82 | ALOX5 (0.44) | ALOX5MEN1KMT2APMP22CNR1 | |
| SCHEMBL21798469 | 0.82 | ALOX5 (0.44) | CYP2C19ALOX5MEN1KMT2APMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2687525-A1 | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 | Boehringer Ingelheim International GmbH (DE) | 2014-01-22 | — | — | EP | disclosed |