Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | APP | P05067 | 5/20 | 0.54 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.54 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.54 |
| ▸ | BCHE | P06276 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 2/20 | 0.52 |
| ▸ | RAD52 | P43351 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13624996 | 0.90 | CYP1A2 (0.54) | KDM4EMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL9232310 | 0.85 | KDM4E (0.64) | KDM4EMEN1KMT2AUSP2ALDH1A1 | |
| SCHEMBL8523769 | 0.81 | KDM4E (0.62) | KDM4EMEN1KMT2AUSP2ALDH1A1 | |
| SCHEMBL9748781 | 0.79 | KDM4E (0.68) | KDM4EMEN1KMT2AUSP2ALDH1A1 | |
| SCHEMBL9387187 | 0.78 | KDM4E (0.69) | KDM4EMEN1KMT2AUSP2ALDH1A1 | |
| SCHEMBL8474173 | 0.78 | BCHE (0.66) | KDM4EHTTGAAAPPBCHE | |
| SCHEMBL9384234 | 0.78 | KDM4E (0.72) | KDM4EMEN1KMT2AUSP2ALDH1A1 | |
| SCHEMBL9382159 | 0.77 | KDM4E (0.65) | KDM4EMEN1KMT2AUSP2ALDH1A1 | |
| SCHEMBL9747358 | 0.76 | KDM4E (0.63) | KDM4EMEN1KMT2AUSP2ALDH1A1 | |
| SCHEMBL8472225 | 0.75 | HTT (0.71) | KDM4EHTTGAABCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612082-B2 | Treating glaucoma; eye disorders | ALLERGAN, INC. (US) | 2009-11-03 | — | — | US | disclosed |
| US-7612082-B2 | Treating glaucoma; eye disorders | ALLERGAN, INC. (US) | 2009-11-03 | — | — | US | disclosed |