Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17898168 | 0.82 | MMP8 (0.32) | MMP8 | |
| SCHEMBL17898147 | 0.81 | CYP2D6 (0.42) | MMP8CA1CA2DGAT1KDM4E | |
| SCHEMBL28292468 | 0.80 | MMP8 (0.37) | MMP8CA1CA2DGAT1 | |
| SCHEMBL27942129 | 0.78 | MMP8 (0.36) | MMP8CA1CA2DGAT1 | |
| SCHEMBL16442445 | 0.77 | MMP8 (0.33) | MMP8CA1CA2 | |
| SCHEMBL769720 | 0.76 | DGAT1 (0.44) | DGAT1KDM4EPKMPRKCA | |
| SCHEMBL10297997 | 0.76 | MMP8 (0.34) | MMP8CA1CA2DGAT1 | |
| SCHEMBL106266 | 0.74 | DGAT1 (0.39) | CA1CA2DGAT1KDM4EPKM | |
| SCHEMBL13951445 | 0.74 | MMP8 (0.33) | MMP8CA1CA2DGAT1 | |
| SCHEMBL6250802 | 0.73 | TSHR (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133264-A2 | MODIFICATION OF THE SURFACE CHEMISTRY OF MACROMOLECULAR SPECIES IN THE PRESENCE OF A CONJUGATED GUANIDINE | POLYRISE (FR) | 2009-11-05 | — | — | WO | disclosed |