SCHEMBL769720

SCHEMBL769720

COC(=O)C(C)(CO)CO

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.44
TSHR P16473 4/20 0.36
KDM4E B2RXH2 1/20 0.35
PKM P14618 1/20 0.35
PRKCA P17252 1/20 0.35
ALDH1A1 P00352 1/20 0.35
KCNN4 O15554 1/20 0.34
HSD17B10 Q99714 1/20 0.33
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
TET2 Q6N021 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C19 P33261 1/20 0.32
HIF1A Q16665 1/20 0.32
GLS O94925 1/20 0.32
SRC P12931 1/20 0.31
RECQL P46063 1/20 0.31
KEAP1 Q14145 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL106266 0.87 DGAT1 (0.39) DGAT1TSHRKDM4EPKMPRKCA
SCHEMBL13224506 0.86 DGAT1 (0.35) DGAT1KDM4EPKMPRKCA
SCHEMBL23095205 0.86 DGAT1 (0.35) DGAT1KDM4EPKMPRKCA
SCHEMBL13224507 0.86 DGAT1 (0.35) DGAT1KDM4EPKMPRKCA
SCHEMBL16359610 0.86 DGAT1 (0.40) DGAT1
SCHEMBL10535565 0.85 DGAT1 (0.38) DGAT1TSHRKDM4EPKMPRKCA
SCHEMBL15494536 0.85 DGAT1 (0.38) DGAT1TSHRKDM4EPKMPRKCA
SCHEMBL16317719 0.84 DGAT1 (0.34) DGAT1KDM4EPKMPRKCA
Lactic Acid SCHEMBL8871139 0.84 TP53 (0.46) DGAT1PRKCAKCNN4
SCHEMBL8871143 0.84 TSHR (0.39) DGAT1TSHRKDM4EALDH1A1KCNN4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 292 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122010858-A Flame-retardant polyhydroxy melamine derivative and preparation method thereof 四川金象赛瑞化工股份有限公司 2026-05-12 CN claimed
CN-119638969-A Degradable aromatic polyester polymer and synthesis method thereof 青岛大学 2025-03-18 CN claimed
US-20240174793-A1 DENDRITIC POLYMER, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF Sinopec Petroleum Engineering Technology Research Institute Co., Ltd. (CN) 2024-05-30 US claimed
EP-4296293-A1 DENDRITIC POLYMER, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF China Petroleum & Chemical Corporation (CN) 2023-12-27 EP claimed
CN-114989438-B Polyester dendritic polymer and preparation method and application thereof 中国石油化工股份有限公司 2023-10-24 CN claimed
CN-114940864-B Kindergarten wall based on novel erasable coating 南通市建筑设计研究院有限公司 2023-08-29 CN claimed
WO-2022255845-A1 NOVEL ERGOSTENOL DERIVATIVE AND USE THEREOF 에스티팜 주식회사 2022-12-08 WO claimed
CN-114989438-A Polyester dendritic polymer and preparation method and application thereof 中国石油化工股份有限公司 2022-09-02 CN claimed
CN-114940864-A Infant garden wall surface based on novel erasable coating 南通市建筑设计研究院有限公司 2022-08-26 CN claimed
CN-100400567-C Method for producing polyetherols BASF AG (DE) 2008-07-09 CN claimed
US-20050148802-A1 Method for producing polyetherols BASF AKTIENGESELLSCHAFT 2005-07-07 US claimed
CN-1585736-A Method for producing (meth)acrylic acid esters of polyhydric alcohols BASF AG (DE) 2005-02-23 CN claimed
US-20050010065-A1 Method for producing (meth) acrylic acid esters of polyhydric alcohols BASF AKTIENGESELLSCHAFT (DE) 2005-01-13 US claimed
CN-1518567-A Linear block polymer ������������� 2004-08-04 CN claimed
CN-1460108-A Water soluble rapamycin esters WYETH CORP (US) 2003-12-03 CN claimed
EP-0866816-B1 LINEAR BLOCK POLYMER COMPRISING UREA AND URETHANE GROUPS, METHOD FOR THE PRODUCTION OF LINEAR BLOCK POLYMERS AND USE OF THE BLOCK POLYMERS AS IMPLANTS ARTIMPLANT DEV ARTDEV AB (SE) 2001-05-30 EP claimed
US-6210441-B1 BIOLOGICALLY DEGRADABLE AND CAN BE EXCRETED FROM A HUMAN BODY ARTIMPLANT DEVELOPMENT ARTDEV AB (SE) 2001-04-03 US claimed
CN-1214057-A Linear block polymer comprising urea and urethane groups, method for prepn. of linear block polymers and use of block polymers as implants ATEM POLYRAND AB (SE) 1999-04-14 CN claimed
EP-0866816-A1 LINEAR BLOCK POLYMER COMPRISING UREA AND URETHANE GROUPS, METHOD FOR THE PRODUCTION OF LINEAR BLOCK POLYMERS AND USE OF THE BLOCK POLYMERS AS IMPLANTS Artimplant Development Artdev AB (SE) 1998-09-30 EP claimed
WO-1997022643-A1 LINEAR BLOCK POLYMER COMPRISING UREA AND URETHANE GROUPS, METHOD FOR THE PRODUCTION OF LINEAR BLOCK POLYMERS AND USE OF THE BLOCK POLYMERS AS IMPLANTS ARTIMPLANT DEVELOPMENT ARTDEV AB (SE) 1997-06-26 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050010065-A1 Method for producing (meth) acrylic acid esters of polyhydric alcohols ADH1A, ADH1C, ADH5 DGAT1 1563/4885TSHR 2220/4885KDM4E 1840/4885
US-20050148802-A1 Method for producing polyetherols ADH1A, ADH1C, ADH5 DGAT1 92/4885TSHR 3289/4885KDM4E 1319/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.