Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 13/20 | 0.49 |
| ▸ | RXRB | P28702 | 10/20 | 0.49 |
| ▸ | RARB | P10826 | 9/20 | 0.49 |
| ▸ | RARG | P13631 | 8/20 | 0.49 |
| ▸ | RXRG | P48443 | 6/20 | 0.49 |
| ▸ | RARA | P10276 | 6/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.45 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1360287 | 1.00 | RXRA (0.49) | RXRARXRBRARBRARGRXRG | |
| SCHEMBL9721391 | 0.86 | OPRM1 (0.41) | RXRARXRBRARBRARGRXRG | |
| SCHEMBL13625257 | 0.84 | TP53 (0.44) | RXRARXRBRARBRARGRXRG | |
| SCHEMBL5847673 | 0.84 | RARB (0.58) | RXRARXRBRARBRARGRXRG | |
| SCHEMBL10834419 | 0.82 | RARA (0.64) | RXRARARBRARGRARACYP1A2 | |
| SCHEMBL12014319 | 0.81 | DRD2 (0.47) | TP53CYP1A2CYP3A4ALDH1A1LMNA | |
| Methane SCHEMBL10834484 | 0.80 | RARA (0.62) | RXRARARBRARGRARACYP1A2 | |
| SCHEMBL2003721 | 0.79 | OPRM1 (0.37) | RXRARXRBRARBRARGRXRG | |
| SCHEMBL29900519 | 0.79 | OPRM1 (0.37) | RXRARXRBRARBRARGRXRG | |
| SCHEMBL3264817 | 0.79 | OPRM1 (0.37) | RXRARXRBRARBRARGRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543430-A1 | SYNTHESIS OF TETRAHYDRONAPHTHALENOLS AND USES THEREOF | IO Therapeutics, Inc. (US) | 2025-04-30 | — | — | EP | disclosed |
| WO-2024006732-A1 | SYNTHESIS OF TETRAHYDRONAPHTHALENOLS AND USES THEREOF | Io Therapeutics, Inc. (US) | 2024-01-04 | — | — | WO | disclosed |