Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.51 |
| ▸ | DAO | P14920 | 3/20 | 0.45 |
| ▸ | ABL1 | P00519 | 6/20 | 0.40 |
| ▸ | SRC | P12931 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.38 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13625357 | 0.86 | ABL1 (0.42) | ABL1SRCHRH4 | |
| SCHEMBL17324213 | 0.83 | ABL1 (0.56) | ABL1SRC | |
| SCHEMBL31296111 | 0.81 | SMAD3 (0.50) | PIN1DAOABL1SRCKDM4E | |
| SCHEMBL5218804 | 0.80 | KDM4E (0.57) | ABL1SRCKDM4EMAPTHPGD | |
| SCHEMBL15738800 | 0.79 | DAO (0.45) | PIN1DAOABL1SRCKDM4E | |
| SCHEMBL16592793 | 0.79 | TSHR (0.46) | PIN1DAOABL1SRCKDM4E | |
| SCHEMBL297192 | 0.79 | KDM4E (0.51) | PIN1DAOABL1SRCKDM4E | |
| SCHEMBL2106960 | 0.79 | F7 (0.56) | PIN1DAOABL1SRCKDM4E | |
| SCHEMBL13180937 | 0.79 | ALDH1A1 (0.43) | DAOABL1SRCKDM4EHPGD | |
| SCHEMBL29722116 | 0.79 | ALDH1A1 (0.43) | DAOABL1SRCKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240228504-A1 | SUBSTITUTED TRICYCLIC AMIDES, ANALOGUES THEREOF, AND METHODS USING SAME | ARBUTUS BIOPHARMA CORPORATION (CA) | 2024-07-11 | — | — | US | disclosed |
| WO-2021110076-A1 | OXAMIDE DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | 深圳信立泰药业股份有限公司 | 2021-06-10 | — | — | WO | disclosed |
| US-10023557-B2 | Therapeutic inhibitory compounds | LIFESCI PHARMACEUTICALS, INC. (BB) | 2018-07-17 | — | — | US | disclosed |
| US-20170029406-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | ATTUNE PHARMACEUTICALS, INC. | 2017-02-02 | — | — | US | disclosed |
| US-7622466-B2 | Azaindole-2-carboxamide derivatives | HOFFMAN-LA ROCHE INC. (US) | 2009-11-24 | — | — | US | disclosed |
| US-20090005379-A1 | Azaindole-2-Carboxamide Derivatives | HOFFMANN-LA ROCHE, INC. | 2009-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170029406-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | KLKB1, SERPINB1, SERPINE1 | PIN1 2559/4885DAO 2963/4885ABL1 878/4885 |
| US-10023557-B2 | Therapeutic inhibitory compounds | KLKB1, SERPINB1, SERPINE1 | PIN1 2559/4885DAO 2963/4885ABL1 878/4885 |
| US-20240228504-A1 | SUBSTITUTED TRICYCLIC AMIDES, ANALOGUES THEREOF, AND METHODS USING SAME | SLC10A1, NR1H4, SLC10A2 | PIN1 70/4885DAO 69/4885ABL1 931/4885 |
| US-20090005379-A1 | Azaindole-2-Carboxamide Derivatives | HRH3, HRH4, H1-5 | PIN1 3709/4885DAO 2638/4885ABL1 524/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.