Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.64 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.64 |
| ▸ | MMP1 | P03956 | 2/20 | 0.57 |
| ▸ | MMP2 | P08253 | 2/20 | 0.57 |
| ▸ | MMP9 | P14780 | 2/20 | 0.57 |
| ▸ | MMP12 | P39900 | 2/20 | 0.57 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.51 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5334298 | 0.88 | MMP1 (0.63) | MMP1MMP2MMP9MMP12MRGPRX4 | |
| SCHEMBL27957224 | 0.82 | MMP1 (0.56) | MMP1MMP2MMP9MMP12MRGPRX4 | |
| SCHEMBL4314829 | 0.81 | KMT2A (0.68) | PRKCAPRKCDKDM4EALDH1A1MAPT | |
| SCHEMBL27957113 | 0.80 | MMP1 (0.54) | MMP1MMP2MMP9MMP12MRGPRX4 | |
| SCHEMBL13625843 | 0.80 | PRKCA (0.67) | PRKCAPRKCDMMP1MMP2MMP9 | |
| SCHEMBL15014006 | 0.80 | MMP1 (0.56) | MMP1MMP2MMP9MMP12MRGPRX4 | |
| SCHEMBL31326237 | 0.79 | MMP1 (0.61) | MMP1MMP2MMP9MMP12MRGPRX4 | |
| SCHEMBL28556983 | 0.79 | MMP1 (0.61) | MMP1MMP2MMP9MMP12MRGPRX4 | |
| SCHEMBL13625637 | 0.78 | PRKCA (0.61) | PRKCAPRKCDKDM4EALDH1A1MAPT | |
| SCHEMBL1421428 | 0.78 | KMT2A (0.65) | MMP1MMP2MMP9MMP12MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009136001-A1 | PROTEIN KINASE MODULATING AGENTS | TUOMINEN RAIMO (FI) | 2009-11-12 | — | — | WO | disclosed |