Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.61 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4625337 | 0.80 | RXFP1 (0.56) | MAPTLMNAKMT2AMEN1PKM | |
| SCHEMBL7203836 | 0.80 | RAB9A (0.60) | MAPTLMNAKMT2AMEN1PKM | |
| SCHEMBL2825416 | 0.80 | MAPT (0.69) | MAPTLMNAKMT2AMEN1PKM | |
| SCHEMBL5335470 | 0.79 | KMT2A (0.60) | MAPTLMNAKMT2APKMALDH1A1 | |
| SCHEMBL11632216 | 0.79 | RAB9A (0.62) | MAPTLMNAKMT2AMEN1PKM | |
| SCHEMBL13625640 | 0.78 | PRKCA (0.64) | PRKCAPRKCDMAPTPKMRXFP1 | |
| SCHEMBL4314829 | 0.78 | KMT2A (0.68) | PRKCAPRKCDMAPTLMNAKMT2A | |
| SCHEMBL6762850 | 0.78 | LMNA (0.57) | MAPTLMNAKMT2AMEN1PKM | |
| SCHEMBL17769827 | 0.78 | MAPT (0.64) | MAPTLMNAKMT2AMEN1PKM | |
| SCHEMBL13625843 | 0.78 | PRKCA (0.67) | PRKCAPRKCDMAPTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009136001-A1 | PROTEIN KINASE MODULATING AGENTS | TUOMINEN RAIMO (FI) | 2009-11-12 | — | — | WO | disclosed |