Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.67 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.67 |
| ▸ | MMP1 | P03956 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.56 |
| ▸ | MMP9 | P14780 | 1/20 | 0.56 |
| ▸ | MMP12 | P39900 | 1/20 | 0.56 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | RXRB | P28702 | 1/20 | 0.49 |
| ▸ | RXRG | P48443 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | AGXT | P21549 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4314829 | 0.83 | KMT2A (0.68) | PRKCAPRKCDSLC6A2SLC6A3KMT2A | |
| SCHEMBL1129557 | 0.82 | LMNA (0.66) | MMP1MMP2MMP9MMP12HCAR2 | |
| SCHEMBL27636542 | 0.82 | KMT2A (0.67) | MMP1MMP2MMP9MMP12HCAR2 | |
| SCHEMBL12879193 | 0.81 | MMP2 (0.54) | MMP1MMP2MMP9MMP12HCAR2 | |
| SCHEMBL13625633 | 0.80 | PRKCA (1.00) | PRKCAPRKCDMMP1MMP12HTT | |
| SCHEMBL13625640 | 0.80 | PRKCA (0.64) | PRKCAPRKCDMMP1MMP2MMP9 | |
| SCHEMBL13626190 | 0.79 | PRKCA (0.62) | PRKCAPRKCDSLC6A2SLC6A3KMT2A | |
| SCHEMBL31738263 | 0.78 | MMP1 (0.54) | MMP1MMP2MMP9MMP12HCAR2 | |
| SCHEMBL31738256 | 0.78 | MMP1 (0.54) | MMP1MMP2MMP9MMP12HCAR2 | |
| SCHEMBL13625637 | 0.78 | PRKCA (0.61) | PRKCAPRKCDHTTMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009136001-A1 | PROTEIN KINASE MODULATING AGENTS | TUOMINEN RAIMO (FI) | 2009-11-12 | — | — | WO | disclosed |