Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.39 |
| ▸ | GABRE | P78334 | 1/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.39 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.39 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.39 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.39 |
| ▸ | PRKCA | P17252 | 3/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13625641 | 0.80 | PRKCA (0.42) | PRKCAPRKCDDRD2DRD4 | |
| SCHEMBL14899908 | 0.78 | FOLH1 (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL3431890 | 0.71 | AOC3 (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL18280143 | 0.70 | CHRNB2 (0.49) | HDAC3HDAC1HDAC2DRD2DRD4 | |
| SCHEMBL20369182 | 0.70 | JMJD6 (0.47) | DRD2DRD4 | |
| SCHEMBL3431892 | 0.70 | HDAC3 (0.38) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL19628365 | 0.70 | TP53 (0.45) | DRD2DRD4 | |
| SCHEMBL4569725 | 0.69 | ALDH1A1 (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2197487 | 0.69 | ALDH1A1 (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6914624 | 0.69 | AOC3 (0.39) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009136001-A1 | PROTEIN KINASE MODULATING AGENTS | TUOMINEN RAIMO (FI) | 2009-11-12 | — | — | WO | disclosed |