Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 3/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.41 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.40 |
| ▸ | THRA | P10827 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20369182 | 0.88 | JMJD6 (0.47) | LMNAJMJD6PARP15PARP10EGFR | |
| SCHEMBL27255751 | 0.86 | MEN1 (0.44) | LMNAJMJD6PARP15PARP10MEN1 | |
| SCHEMBL19399040 | 0.81 | DRD2 (0.44) | JMJD6PARP15PARP10DRD2DRD4 | |
| SCHEMBL10087721 | 0.80 | LCK (0.43) | LMNAJMJD6PARP15PARP10EGFR | |
| SCHEMBL3468807 | 0.80 | PARP15 (0.54) | LMNAJMJD6PARP15PARP10DRD2 | |
| SCHEMBL13625651 | 0.80 | GABRP (0.39) | PRKCAPRKCDDRD2DRD4 | |
| SCHEMBL28780695 | 0.79 | SERPINE1 (0.57) | LMNAEGFRTDP1 | |
| SCHEMBL16247834 | 0.79 | L3MBTL1 (0.40) | JMJD6MEN1KMT2APDE1C | |
| SCHEMBL13625650 | 0.78 | SERPINE1 (0.49) | PRKCAPRKCDLMNAMEN1KMT2A | |
| SCHEMBL27786755 | 0.78 | SERPINE1 (0.58) | LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009136001-A1 | PROTEIN KINASE MODULATING AGENTS | TUOMINEN RAIMO (FI) | 2009-11-12 | — | — | WO | disclosed |