Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | ALB | P02768 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.54 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.54 |
| ▸ | TUBB | P07437 | 1/20 | 0.54 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.54 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.54 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.54 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.54 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.54 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.54 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.54 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.54 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.54 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL116377 | 0.85 | ALDH1A1 (0.49) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL9750374 | 0.82 | AADAT (0.58) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL116382 | 0.82 | AADAT (0.58) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL116358 | 0.81 | LMNA (0.52) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL10424572 | 0.80 | ALDH1A1 (0.57) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL115020 | 0.80 | ALDH1A1 (0.49) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL9615256 | 0.78 | KCNH2 (0.56) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL584219 | 0.77 | AADAT (0.52) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL584176 | 0.77 | AADAT (0.52) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL2527668 | 0.77 | AADAT (0.52) | KDM4EALDH1A1HPGDHSD17B10ALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009137130-A2 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | ACHAOGEN, INC. (US) | 2009-11-12 | — | — | WO | disclosed |