Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.59 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.47 |
| ▸ | RXRA | P19793 | 2/20 | 0.47 |
| ▸ | RXRB | P28702 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6669799 | 0.85 | TDP1 (0.60) | PRKCAPRKCDNPC1RAB9ANR4A2 | |
| SCHEMBL20679874 | 0.85 | NPC1 (0.55) | NPC1RAB9ANR4A2RXRARXRB | |
| SCHEMBL10392942 | 0.84 | KMT2A (0.65) | NPC1RAB9ANR4A2RXRARXRB | |
| SCHEMBL21098985 | 0.81 | NPC1 (0.51) | NPC1RAB9AEPHX2NR4A2RXRA | |
| SCHEMBL31715823 | 0.80 | TDP1 (0.69) | NPC1RAB9ANR4A2RXRARXRB | |
| SCHEMBL11002185 | 0.80 | KMT2A (0.74) | NPC1RAB9ANR4A2RXRARXRB | |
| SCHEMBL4314829 | 0.80 | KMT2A (0.68) | PRKCAPRKCDNPC1RAB9ATDP1 | |
| SCHEMBL8581850 | 0.79 | TDP1 (0.54) | PRKCAPRKCDNPC1RAB9ANR4A2 | |
| SCHEMBL8839073 | 0.79 | RXRA (0.68) | NPC1RAB9AEPHX2NR4A2RXRA | |
| SCHEMBL18320469 | 0.77 | KMT2A (0.69) | NPC1RAB9ANR4A2RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009136001-A1 | PROTEIN KINASE MODULATING AGENTS | TUOMINEN RAIMO (FI) | 2009-11-12 | — | — | WO | disclosed |