SCHEMBL6669799

SCHEMBL6669799

CC(C)(C)c1ccc(COC(=O)c2cccc(C(=O)OCc3ccc(C(C)(C)C)cc3)c2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.60
RAB9A P51151 5/20 0.58
NPC1 O15118 3/20 0.58
NR4A2 P43354 2/20 0.58
NR4A1 P22736 1/20 0.58
NR4A3 Q92570 1/20 0.58
KMT2A Q03164 4/20 0.53
SLC6A2 P23975 1/20 0.53
SLC6A3 Q01959 1/20 0.53
RXRA P19793 1/20 0.49
RXRB P28702 1/20 0.49
MEN1 O00255 3/20 0.49
SMN1; SMN2 Q16637 4/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
PRKCA P17252 1/20 0.48
PRKCD Q05655 1/20 0.48
HTT P42858 1/20 0.47
MAPT P10636 2/20 0.46
KDM4E B2RXH2 2/20 0.46
ALDH1A1 P00352 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8581850 0.90 TDP1 (0.54) TDP1RAB9ANPC1NR4A2NR4A1
SCHEMBL31715823 0.89 TDP1 (0.69) TDP1RAB9ANPC1NR4A2NR4A1
SCHEMBL10392942 0.87 KMT2A (0.65) TDP1RAB9ANPC1NR4A2NR4A1
SCHEMBL13538344 0.85 TDP1 (0.63) TDP1RAB9ANPC1NR4A2NR4A1
SCHEMBL13625842 0.85 PRKCA (0.59) TDP1RAB9ANPC1NR4A2NR4A1
SCHEMBL20679874 0.84 NPC1 (0.55) TDP1RAB9ANPC1NR4A2NR4A1
SCHEMBL11002185 0.83 KMT2A (0.74) TDP1RAB9ANPC1NR4A2KMT2A
SCHEMBL18320469 0.83 KMT2A (0.69) TDP1RAB9ANPC1NR4A2KMT2A
SCHEMBL6653627 0.82 L3MBTL1 (0.61) TDP1RAB9ANPC1KMT2ASLC6A2
SCHEMBL3673244 0.82 RAB9A (0.52) TDP1RAB9ANPC1KMT2ASLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1004621-B1 GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME TEIJIN CHEMICALS LTD (JP) 2004-09-15 EP disclosed
US-6485657-B1 Gamma-ray stabilizer and thermoplastic polymer compound including the said stabilizer TEIJIN, LIMITED (JP) 2002-11-26 US disclosed
EP-1004621-A1 GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME TEIJIN LIMITED (JP) 2000-05-31 EP disclosed