Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.52 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.52 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.46 |
| ▸ | PRKCA | P17252 | 1/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6669799 | 0.90 | TDP1 (0.60) | TDP1RAB9ANPC1NR4A2NR4A1 | |
| SCHEMBL318600 | 0.84 | TDP1 (0.71) | TDP1RAB9ANPC1SLC6A2SLC6A3 | |
| SCHEMBL31715823 | 0.83 | TDP1 (0.69) | TDP1RAB9ANPC1NR4A2NR4A1 | |
| SCHEMBL13538344 | 0.82 | TDP1 (0.63) | TDP1RAB9ANPC1NR4A2NR4A1 | |
| SCHEMBL10392942 | 0.81 | KMT2A (0.65) | TDP1RAB9ANPC1NR4A2NR4A1 | |
| SCHEMBL8581235 | 0.81 | RAB9A (0.74) | TDP1RAB9ANPC1SLC6A2SLC6A3 | |
| SCHEMBL18320469 | 0.80 | KMT2A (0.69) | TDP1RAB9ANPC1NR4A2SLC6A2 | |
| SCHEMBL13625842 | 0.79 | PRKCA (0.59) | TDP1RAB9ANPC1NR4A2NR4A1 | |
| SCHEMBL20679874 | 0.79 | NPC1 (0.55) | TDP1RAB9ANPC1NR4A2NR4A1 | |
| SCHEMBL1198044 | 0.78 | CYP4F2 (0.66) | RAB9ANPC1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712367-A | COUPLING WITH LIPOPHILIC SUBSTITUENT | RHONE-POULENC CHIMIE (FR) | 1998-01-27 | — | — | US | disclosed |