Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.62 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.62 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4030534 | 0.86 | GSK3B (0.53) | FFAR1FFAR4MRGPRX4TDP1SLC6A2 | |
| SCHEMBL29248378 | 0.81 | MRGPRX4 (0.53) | FFAR1FFAR4MRGPRX4TDP1SLC6A2 | |
| SCHEMBL4314829 | 0.79 | KMT2A (0.68) | PRKCAPRKCDTDP1SLC6A2SLC6A3 | |
| SCHEMBL13625843 | 0.79 | PRKCA (0.67) | PRKCAPRKCDMRGPRX4TDP1SLC6A2 | |
| SCHEMBL6330377 | 0.79 | TDP1 (0.63) | TDP1SLC6A2SLC6A3KMT2AKDM4E | |
| SCHEMBL16150588 | 0.77 | ALDH1A1 (0.56) | FFAR1FFAR4MRGPRX4ALDH1A1GSK3B | |
| SCHEMBL16439821 | 0.77 | FFAR1 (0.53) | FFAR1FFAR4MRGPRX4CYP19A1CYP11B1 | |
| SCHEMBL2659356 | 0.77 | ALDH1A1 (0.56) | FFAR1FFAR4MRGPRX4ALDH1A1GSK3B | |
| SCHEMBL14783862 | 0.77 | FFAR1 (0.53) | FFAR1FFAR4MRGPRX4CYP19A1CYP11B1 | |
| SCHEMBL13625633 | 0.77 | PRKCA (1.00) | PRKCAPRKCDFFAR1FFAR4MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009136001-A1 | PROTEIN KINASE MODULATING AGENTS | TUOMINEN RAIMO (FI) | 2009-11-12 | — | — | WO | disclosed |